Evidence map›Paper›PMID 31276677›Full record

ArticleThe Journal of investigative dermatology2020

Conditional Alox12b Knockout: Degradation of the Corneocyte Lipid Envelope in a Mouse Model of Autosomal Recessive Congenital Ichthyoses.

Peter Krieg, Angela Dick, Susanne Latzko, Sabine Rosenberger, Jason Meyer, Debra Crumrine, Thomas Hielscher, Peter M Elias, Manfred Rauh, Holm Schneider

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Peter KriegMolecular Diagnostics of Oncogenic Infections, German Cancer Research Center, Heidelberg, Germany.
Angela DickDepartment of Pediatrics, University of Erlangen-Nürnberg, Erlangen, Germany.
Susanne LatzkoMolecular Diagnostics of Oncogenic Infections, German Cancer Research Center, Heidelberg, Germany.
Sabine RosenbergerMolecular Diagnostics of Oncogenic Infections, German Cancer Research Center, Heidelberg, Germany.
Jason MeyerDermatology Service, VA Medical Center, San Francisco, California, USA; Department of Dermatology, University of California, San Francisco, California, USA.
Debra CrumrineDermatology Service, VA Medical Center, San Francisco, California, USA; Department of Dermatology, University of California, San Francisco, California, USA.
Thomas HielscherDepartment of Biostatistics, German Cancer Research Center, Heidelberg, Germany.
Peter M EliasDermatology Service, VA Medical Center, San Francisco, California, USA; Department of Dermatology, University of California, San Francisco, California, USA.
Manfred RauhDepartment of Pediatrics, University of Erlangen-Nürnberg, Erlangen, Germany.
Holm SchneiderDepartment of Pediatrics, University of Erlangen-Nürnberg, Erlangen, Germany. Electronic address: holm.schneider@uk-erlangen.de.

Funding

UCSF Dermatology Training GrantT32AR007175 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Wilson Liao, Michael David Rosenblum · 1986 to 2026
$6.1M
NIAMS NIH HHS T32 AR007175
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsArachidonate 12-LipoxygenaseDisease Models, AnimalGenes, RecessiveHumansIchthyosis, LamellarLipid PeroxidationMiceMice, KnockoutMutationSkinSkin Physiological PhenomenaALOX12B protein, humanAlox12b protein, mouseArachidonate 12-Lipoxygenase

Identifiers

PMID31276677
PMCPMC7111211

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.