ArticlePloS one2019
Sensitive and rapid detection of cholera toxin subunit B using magnetic frequency mixing detection.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Magnetic nanoparticles for cancer theranostics.Biomedical physics & engineering express · 2026Review
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- Fundamentals and Applications of Dual-Frequency Magnetic Particle Spectroscopy: Review for Biomedicine and Materials Characterization.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Miniaturized Pathogen Detection System Using Magnetic Nanoparticles and Microfluidics Technology.Micromachines · 2024Article
- DNA Sensor for the Detection ofInternational journal of molecular sciences · 2023Article
- Label-free, real-time monitoring of membrane binding events at zeptomolar concentrations using frequency-locked optical microresonators.bioRxiv : the preprint server for biology · 2023Article
- Magnetic Particle Spectroscopy for Point-of-Care: A Review on Recent Advances.Sensors (Basel, Switzerland) · 2023Review
- Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source.Sensors (Basel, Switzerland) · 2022Article
- Magnetic nanoparticles and magnetic particle spectroscopy-based bioassays: a 15 year recap.Nano futures · 2022Article
- On-site detection of food and waterborne bacteria - current technologies, challenges, and future directions.Trends in food science & technology · 2021Article
- Multiplex Detection of Magnetic Beads Using Offset Field Dependent Frequency Mixing Magnetic Detection.Sensors (Basel, Switzerland) · 2021Article
- Comparative Modeling of Frequency Mixing Measurements of Magnetic Nanoparticles Using Micromagnetic Simulations and Langevin Theory.Nanomaterials (Basel, Switzerland) · 2021Article
- Investigation of Commercial Iron Oxide Nanoparticles: Structural and Magnetic Property Characterization.ACS omega · 2021Article
- Development of Fast and Portable Frequency Magnetic Mixing-Based Serological SARS-CoV-2-Specific Antibody Detection Assay.Frontiers in microbiology · 2021Article
- A Novel Method for Antibiotic Detection in Milk Based on Competitive Magnetic Immunodetection.Foods (Basel, Switzerland) · 2020Article
- Review
- Sensitive Aflatoxin B1 Detection Using Nanoparticle-Based Competitive Magnetic Immunodetection.Toxins · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cholera is a life-threatening disease caused by the cholera toxin (CT) as produced by some Vibrio cholerae serogroups. In this research we present a method which directly detects the toxin's B subunit (CTB) in drinking water. For this purpose we performed a magnetic sandwich immunoassay inside a 3D immunofiltration column. We used two different commercially available antibodies to capture CTB and for binding to superparamagnetic beads. ELISA experiments were performed to select the antibody combination. The beads act as labels for the magnetic frequency mixing detection technique. We show that the limit of detection depends on the type of magnetic beads. A nonlinear Hill curve was fitted to the calibration measurements by means of a custom-written python software. We achieved a sensitive and rapid detection of CTB within a broad concentration range from 0.2 ng/ml to more than 700 ng/ml.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.