Evidence map›Paper›PMID 31276439›Full record

ArticleAutophagy2020

Subnanometer resolution cryo-EM structure of

Louis Tung Faat Lai, Chuanyang Yu, Jan Siu Kei Wong, Ho Sing Lo, Samir Benlekbir, Liwen Jiang, Wilson Chun Yu Lau

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Guideline
  2. Mechanisms of autophagosome formation.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025
    Review
  3. Review
  4. CaScientific reports · 2024
    Article
  5. Article
  6. Autophagy in plants.Autophagy reports · 2024
    Review
  7. Determination of the Cryo-EM Structure of ATG9 from Arabidopsis thaliana.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Lipid Transport from Endoplasmic Reticulum to Autophagic Membranes.Cold Spring Harbor perspectives in biology · 2022
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Louis Tung Faat LaiCentre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Shatin, China.ORCID 0000-0003-1413-7035
Chuanyang YuCentre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Shatin, China.
Jan Siu Kei WongCentre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Shatin, China.
Ho Sing LoCentre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Shatin, China.
Samir BenlekbirMolecular Medicine Program, The Hospital for Sick Children, Toronto, Canada.
Liwen JiangCentre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Shatin, China.
Wilson Chun Yu LauCentre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Shatin, China.ORCID 0000-0002-3069-8513
Chinese University of Hong Kong · HKHospital for Sick Children · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macroautophagy/autophagy is an essential process for the maintenance of cellular homeostasis by recycling macromolecules under normal and stress conditions. ATG9 (autophagy related 9) is the only integral membrane protein in the autophagy core machinery and has a central role in mediating autophagosome formation. In cells, ATG9 exists on mobile vesicles that traffic to the growing phagophore, providing an essential membrane source for the formation of autophagosomes. Here we report the three-dimensional structure of ATG9 from

Indexed as

Cryoelectron MicroscopyNanotechnologyArabidopsisArabidopsis ProteinsAutophagy-Related ProteinsMembrane ProteinsModels, MolecularProtein MultimerizationProtein Structure, SecondaryStructural Homology, ProteinAPG9 protein, ArabidopsisArabidopsis ProteinsAutophagy-Related ProteinsMembrane ProteinsATG9autophagosomeautophagycryo-electron microscopysingle particle

Identifiers

PMID31276439
PMCPMC6999609
OpenAlexW2954965931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.