Evidence map›Paper›PMID 31276030›Full record

ReviewBMJ open ophthalmology2019

Metagenomics in ophthalmology: current findings and future prospectives.

Davide Borroni, Vito Romano, Stephen B Kaye, Tobi Somerville, Luca Napoli, Adriano Fasolo, Paola Gallon, Diego Ponzin, Alfonso Esposito, Stefano Ferrari

Erratum issuedAbstract readReview
In one paragraph

Review in BMJ open ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Metagenomic next-generation sequencing for comprehensive pathogen detection in intraocular infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Next-Generation Sequencing of the Human Aqueous Humour Microbiome.International journal of molecular sciences · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Diagnosis ofDiagnostics (Basel, Switzerland) · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Editorial: Imaging in Ophthalmology.Journal of clinical medicine · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Davide BorroniSt Paul's Eye Unit, Department of Corneal and External Eye Diseases, Royal Liverpool University Hospital, Liverpool, United Kingdom info.borroni@gmail.com.ORCID http://orcid.org/0000-0001-6952-5647
Vito RomanoSt Paul's Eye Unit, Department of Corneal and External Eye Diseases, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Stephen B KayeSt Paul's Eye Unit, Department of Corneal and External Eye Diseases, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Tobi SomervilleSt Paul's Eye Unit, Department of Corneal and External Eye Diseases, Royal Liverpool University Hospital, Liverpool, United Kingdom.
Luca NapoliDipartimento di Specialità Medico-Chirurgiche, Scienze Radiologiche e Sanita Pubblica, Universita degli Studi di Brescia, Brescia, Italy.
Adriano FasoloFondazione Banca Degli Occhi Del Veneto Onlus, Zelarino, Venezia, Italy.
Paola GallonFondazione Banca Degli Occhi Del Veneto Onlus, Zelarino, Venezia, Italy.
Diego PonzinFondazione Banca Degli Occhi Del Veneto Onlus, Zelarino, Venezia, Italy.
Alfonso EspositoCentre for Integrative Biology (CIBIO), Trento University, Trento, Italy.
Stefano FerrariFondazione Banca Degli Occhi Del Veneto Onlus, Zelarino, Venezia, Italy.

Funding

Medical Research Council MR/S022104/1
6 · The paper itself

Abstract

Less than 1% of all microorganisms of the available environmental microbiota can be cultured with the currently available techniques. Metagenomics is a new methodology of high-throughput DNA sequencing, able to provide taxonomic and functional profiles of microbial communities without the necessity to culture microbes in the laboratory. Metagenomics opens to a 'hypothesis-free' approach, giving important details for future research and treatment of ocular diseases in ophthalmology, such as ocular infection and ocular surface diseases.

Indexed as

corneaeyemetagenomicsmicrobiomeocular surfaceophthalmologysequencing

Identifiers

PMID31276030
PMCPMC6557081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.