ReviewFrontiers in medicine2019
Infections in the Elderly Critically-Ill Patients.
Review in Frontiers in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 7 syntheses or guidelines pooled it, 152 citations in OpenAlex.
- Use of Health State Utility Values in Cost-Utility Analyses of Selected Infectious Diseases in Aging Populations: A Systematic Review and Critical Appraisal.PharmacoEconomics - open · 2026Pooled it
- Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis.Aging · 2025Pooled it
- Cellular senescence in acute human infectious disease: a systematic review.Frontiers in aging · 2024Pooled it
- Clinical symptoms, diagnosis, treatment, and outcome of COVID-19-associated encephalitis: A systematic review of case reports and case series.Journal of clinical laboratory analysis · 2022Pooled it
- Risk of antimicrobial-associated organ injury among the older adults: a systematic review and meta-analysis.BMC geriatrics · 2021Pooled it
- Encephalitis as a neurological complication of COVID-19: A systematic review and meta-analysis of incidence, outcomes, and predictors.European journal of neurology · 2021Pooled it
- Stroke as a Neurological Complication of COVID-19: A Systematic Review and Meta-Analysis of Incidence, Outcomes and Predictors.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021Pooled it
- The role of gut microbiome in aging-associated diseases: where do we stand now and how technology will transform the future.Gut microbes · 2026Review
- Article
- Implementing portable, real-time 16S rRNA sequencing in the healthcare sector enhances antimicrobial stewardship.EBioMedicine · 2026Article
- Magnitude and Predictors of Antimicrobial Use-Related Drug Problems in Geriatric Inpatients: Evaluation of Pharmacist Interventions.Current drug safety · 2026Article
- Tocilizumab in German patients with RA: real-world evidence from the noninterventional studies ARATA and ICHIBAN.EULAR rheumatology open · 2026Review
- Assessing the association between elements of health inequalities and the risk of bacterial infection in high-income countries: a systematic scoping review.Access microbiology · 2026Review
- Insights from older adults in North Carolina: Understanding social determinants of health through focus groups.Journal of health equity · 2026Article
- Association between indwelling urinary catheters and the poor prognosis among elderly patients with pulmonary infection.Frontiers in cellular and infection microbiology · 2026Article
- Risk factors associated with mortality in patients with catheter-related and catheter-associated bloodstream infections: a retrospective observational study focused on CVADs and midlines.Antimicrobial resistance and infection control · 2025Observational
- Combining demographic shifts with age-based resistance prevalence to estimate future antimicrobial resistance burden in Europe and implications for targets: A modelling study.PLoS medicine · 2025Article
- Trends in the Antimicrobial Resistance Pattern of Bacterial Gram-Negative Pathogens in Elderly Patients Admitted to the Intensive Care Unit.Microorganisms · 2025Article
- A Host-Protein Test for Differentiating Bacterial From Viral Infection: Diagnostic Accuracy in Elderly Patients.Journal of the American College of Emergency Physicians open · 2025Article
- Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infections are leading causes of morbidity and mortality in the advanced aged. Various factors including immunosenescens, comorbid chronic diseases, and alterations in normal physiological organ functions may modify the frequency and severity of infections in elderly patients. Normal body reactions to ensuing infection, such as increased body temperature, may be blunted in those patients causing difficulties in differential diagnosis between infection and other diseases. In severe infections the respiratory and urinary tracts are the most frequently involved systems which may be accompanied by severe sepsis. Bacteremia and sepsis are also associated with indwelling vascular catheters in the elderly who are admitted to the intensive care unit (ICU). Older patients are more vulnerable to the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.