ArticleFrontiers in bioengineering and biotechnology2019
Analysis and Modeling of Rat Gait Biomechanical Deficits in Response to Volumetric Muscle Loss Injury.
Article in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Running-based rehabilitation does not improve muscle function after volumetric muscle loss despite improving hindlimb weight-bearing asymmetry in mice.Experimental physiology · 2026Article
- Automatic registration of generic bone models for X-ray-based biomechanics: Application to 3D rat hindlimb kinematics and sex-specific gait patterns.Computers in biology and medicine · 2026Article
- Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration.Trends in biotechnology · 2024Article
- Tibial bone strength is negatively affected by volumetric muscle loss injury to the adjacent muscle in male mice.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Resistance wheel running improves contractile strength, but not metabolic capacity, in a murine model of volumetric muscle loss injury.Experimental physiology · 2023Article
- Comprehensive dynamic and kinematic analysis of the rodent hindlimb during over ground walking.Scientific reports · 2022Article
- Retrospective characterization of a rat model of volumetric muscle loss.BMC musculoskeletal disorders · 2022Article
- A musculoskeletal finite element model of rat knee joint for evaluating cartilage biomechanics during gait.PLoS computational biology · 2022Article
- Osseosurface electronics-thin, wireless, battery-free and multimodal musculoskeletal biointerfaces.Nature communications · 2021Article
- Role of Vascular Endothelial Growth Factor and Human Umbilical Vein Endothelial Cells in Designing AnCell journal · 2020Article
- Progressing the field of Regenerative Rehabilitation through novel interdisciplinary interaction.NPJ Regenerative medicine · 2020Article
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Authors and funding
7 authors.
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Abstract
There is currently a substantial volume of research underway to develop more effective approaches for the regeneration of functional muscle tissue as treatment for volumetric muscle loss (VML) injury, but few studies have evaluated the relationship between injury and the biomechanics required for normal function. To address this knowledge gap, the goal of this study was to develop a novel method to quantify the changes in gait of rats with tibialis anterior (TA) VML injuries. This method should be sensitive enough to identify biomechanical and kinematic changes in response to injury as well as during recovery. Control rats and rats with surgically-created VML injuries were affixed with motion capture markers on the bony landmarks of the back and hindlimb and were recorded walking on a treadmill both prior to and post-surgery. Data collected from the motion capture system was exported for
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