Evidence map›Paper›PMID 31275925›Full record

ArticleFrontiers in chemistry2019

Confinement of Suspension-Cultured Cells in Polyethylene Glycol/Polyethylene Oxide-Albumin Aqueous Two-Phase Systems.

Alyne G Teixeira, Alex Kleinman, Rishima Agarwal, Nicky W Tam, Jun Wang, John P Frampton

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alyne G TeixeiraSchool of Biomedical Engineering, Dalhousie University, Halifax, NS, Canada.
Alex KleinmanPomona College, Claremont, CA, United States.
Rishima AgarwalSchool of Biomedical Engineering, Dalhousie University, Halifax, NS, Canada.
Nicky W TamSchool of Biomedical Engineering, Dalhousie University, Halifax, NS, Canada.
Jun WangDepartment of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.
John P FramptonSchool of Biomedical Engineering, Dalhousie University, Halifax, NS, Canada.
Dalhousie University · CAPomona College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aqueous two-phase systems (ATPSs) have numerous applications in separation science, and more recently, in bioassays enabled by the solution micropatterning of cells. The most frequently used ATPS in these applications is the polyethylene glycol (PEG)-dextran (Dex) system, as the polymers that form this ATPS have been extensively characterized in terms of their physicochemical properties. However, in addition to this well-known system, there exist many other ATPSs with properties that may be exploited to improve upon the PEG-dextran system for specific applications. One of these underexplored systems is the ATPS formed from PEG/polyethylene oxide (PEO) and albumin. In this article, we characterize the phase separation of PEG (35 kDa) and polyethylene oxide (PEO) (200, 900, and 4,000 kDa) with bovine serum albumin (BSA). We describe the microscopic emulsion behavior of these systems in the presence of NaCl and compounds (NaHCO

Indexed as

aqueous two-phase systemsbovine serum albumincell partitioningELISpotimmune cellspolyethylene glycolpolyethylene oxide

Identifiers

PMID31275925
PMCPMC6591268
OpenAlexW2950141260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.