Evidence map›Paper›PMID 31275919›Full record

ArticleFrontiers in chemistry2019

Rapid Detection and Quantification of Novel Psychoactive Substances (NPS) Using Raman Spectroscopy and Surface-Enhanced Raman Scattering.

Howbeer Muhamadali, Alexandra Watt, Yun Xu, Malama Chisanga, Abdu Subaihi, Carys Jones, David I Ellis, Oliver B Sutcliffe, Royston Goodacre

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Interpol Review of Drug Analysis 2019-2022.Forensic science international. Synergy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Howbeer MuhamadaliDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Alexandra WattSchool of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom.
Yun XuDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.
Malama ChisangaSchool of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom.
Abdu SubaihiSchool of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom.
Carys JonesSchool of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom.
David I EllisSchool of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom.
Oliver B SutcliffeMANchester DRug Analysis and Knowledge Exchange, Faculty of Science and Engineering, School of Science and the Environment, Manchester Metropolitan University, Manchester, United Kingdom.
Royston GoodacreDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With more than a million seizures of illegal drugs reported annually across Europe, the variety of psychoactive compounds available is vast and ever-growing. The multitude of risks associated with these compounds are well-known and can be life threatening. Hence the need for the development of new analytical techniques and approaches that allow for the rapid, sensitive, and specific quantitative detection and discrimination of such illicit materials, ultimately with portability for field testing, is of paramount importance. The aim of this study was to demonstrate the application of Raman spectroscopy and surface-enhanced Raman scattering (SERS) combined with chemometrics approaches, as rapid and portable techniques for the quantitative detection and discrimination of a wide range of novel psychoactive substances (methcathinone and aminoindane derivatives), both in powder form and in solution. The Raman spectra of the psychoactive compounds provided clear separation and classification of the compounds based on their core chemical structures;

Indexed as

drug detectionpsychoactive compoundsramanSERSspectroscopy

Identifiers

PMID31275919
PMCPMC6593286

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