ArticleJournal of diabetes and metabolic disorders2019
Periodontitis and diabetes interrelationships in rats: biochemical and histopathological variables.
Article in Journal of diabetes and metabolic disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Epithelial Inflammatory iNOS-Nitrate Axis EnhancesInternational journal of molecular sciences · 2026Article
- Article
- Effect of artesunate on cardiovascular complications in periodontitis in a type I diabetes rat model and related mechanisms.Journal of endocrinological investigation · 2023Article
- Comparison of the inflammatory states of serum and gingival crevicular fluid in periodontitis patients with or without type 2 diabetes mellitus.Journal of dental sciences · 2023Article
- The association between oxidative balance score and periodontitis in adults: a population-based study.Frontiers in nutrition · 2023Article
- Expression of Inflammatory Mediators in Periodontitis Over Established Diabetes: an Experimental Study in Rats.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2021Article
- Role of Artesunate on cardiovascular complications in rats with type 1 diabetes mellitus.BMC endocrine disorders · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA two-way relationship between diabetes and periodontitis is now clinically established. Both conditions share common mechanisms of pathogenesis that are related to altered immune-inflammatory responses at local and/or systemic levels. The aim of this study is to investigate whether periodontitis is associated with the development and progression of diabetes and to evaluate the health impact of coexistence of both diseases. MATERIAL AND
methodsMale Sprague Dawley rats (10 weeks old) were randomized into seven groups (
resultsBody weight was significantly decreased (25%) following diabetes induction (
conclusionWhen periodontitis occurs after diabetes it aggravates the symptoms of the two pathologies. When diabetes is induced after periodontitis, no symptoms aggravation is observed for diabetes, although periodontitis gets worse.
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