Evidence map›Paper›PMID 31275813›Full record

ArticleCardiovascular diagnosis and therapy2019

Screening of extra-coronary arteriopathy with magnetic resonance angiography in patients with spontaneous coronary artery dissection: a single-centre experience.

Fernando Macaya, Manuel Moreu, Virginia Ruiz-Pizarro, Carlos H Salazar, Eduardo Pozo, Andrés Aldazábal, Reddy Guerra, Santiago Rosati, Pablo Salinas, Nieves Gonzalo and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Fernando MacayaHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Manuel MoreuHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Virginia Ruiz-PizarroHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Carlos H SalazarHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Eduardo PozoHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Andrés AldazábalHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Reddy GuerraHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Santiago RosatiHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Pablo SalinasHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Nieves GonzaloHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
María J Pérez-VizcaynoHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Leopoldo Pérez de IslaHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Antonio Fernández-OrtizHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Carlos MacayaHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
David AdlamLeicester NIHR Biomedical Research Unit, Glenfield Hospital, Leicester University, Leicester, UK.
Juan ArrazolaHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Javier EscanedHospital Clínico San Carlos, IdISSC, Universidad Complutense, Madrid, Spain.
Hospital Clínico San Carlos · ESInstituto de Investigación Sanitaria del Hospital Clínico San Carlos · ESGlenfield Hospital · GB

Funding

British Heart Foundation PG/13/96/30608
6 · The paper itself

Abstract

backgroundCurrent consensus recommends extended vascular investigation in patients with spontaneous coronary artery dissection (SCAD). We here report our experience with the use of magnetic resonance angiography (MRA) for screening extra-coronary arteriopathy in patients presenting with SCAD.

methodsPatients presenting with SCAD in a Spanish centre underwent prospective contrast-enhanced MRA to assess the cephalic and abdominopelvic arterial territories. Fibromuscular dysplasia (FMD) was diagnosed following European consensus criteria. Other vascular abnormalities were recorded separately. Two vascular radiologists supervised the acquisitions and independently analysed the results for all cases.

resultsForty patients with SCAD [mean age 50.9±8.6 years, 90% (n=36) women] were included in the study, 12 patients declined to participate and 5 were excluded (metallic implanted devices). All enrolled patients underwent the screening protocol without complications. MRA demonstrated at least one extra-coronary vascular abnormality in 16 patients (40%): 5 (12.5%) were diagnosed with FMD, 6 (15%) showed arterial tortuosity, 3 (7.5%) had non-FMD focal stenoses, and 2 (5%) were found to have small aneurysms at the celiac trunk and splenic artery. No intracranial aneurysms were detected. At a mean follow-up of 4±3 years from the index episode, two cases experienced SCAD recurrences, one in a patient with FMD and the other one in a patient with arterial tortuosity. No deaths or strokes occurred.

conclusionsSystematic extended vascular study with MRA was feasible and demonstrated associated extra-coronary arteriopathy in a substantial proportion of patients presenting with SCAD; however, none required additional intervention or led to vascular events. MRA, being a radiation-free modality, may be the preferred method for screening extracoronary arteriopathy in SCAD, a condition primarily affecting young and middle-age women sensitive to the risks of radiation.

Indexed as

Fibromuscular dysplasia (FMD)intracranial aneurysmmagnetic resonance angiography (MRA)spontaneous coronary artery dissection (SCAD)

Identifiers

PMID31275813
PMCPMC6603500
OpenAlexW2946192486

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.