Evidence map›Paper›PMID 31275685›Full record

ArticleCase reports in orthopedics2019

Osteosarcomatous Transformation in the Setting of Mazabraud's Syndrome: A Case Report and Review of the Literature.

Iqbal Multani, Snezana Popovic, Naveen Parasu, Michelle Ghert

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in orthopedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Iqbal MultaniRoyal North Shore Hospital, Reserve Rd, Sydney, New South Wales, Australia.ORCID 0000-0001-7976-3243
Snezana PopovicHamilton Health Sciences, Juravinski Hospital and Cancer Centre, 711 Concession Street, Hamilton, ON, Canada L8V 1C3.
Naveen ParasuHamilton Health Sciences, Juravinski Hospital and Cancer Centre, 711 Concession Street, Hamilton, ON, Canada L8V 1C3.
Michelle GhertHamilton Health Sciences, Juravinski Hospital and Cancer Centre, 711 Concession Street, Hamilton, ON, Canada L8V 1C3.ORCID 0000-0002-4778-4522
Juravinski Hospital · CARoyal North Shore Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMazabraud's Syndrome is a rare condition that is defined by the presence of fibrous dysplasia lesions in the bone and intramuscular myxomas in the soft tissue. Malignant transformation, in the setting of Mazabraud's Syndrome, of the fibrous dysplasia lesions into a sarcomatous neoplasm occurs in less than 1% of cases-with only six previously reported cases. CASE PRESENTATION: Here, we present a 62-year-old Caucasian female who developed an osteosarcoma in a fibrous dysplasia lesion of the proximal femur in the background of Mazabraud's Syndrome. The patient was treated with wide excision and endoprosthetic reconstruction. She declined adjuvant chemotherapy. She is alive without evidence of disease one-year postoperatively.

conclusionPatients with Mazabraud's Syndrome remain at low risk for malignant transformation. However, close monitoring of asymptomatic patients with this condition for radiographic changes in their lesions and/or clinical symptoms is recommended.

Identifiers

PMID31275685
PMCPMC6558611
OpenAlexW2947513926

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.