Evidence map›Paper›PMID 31275628›Full record

ArticleJournal of ophthalmology2019

Inverted ILM Flap for the Treatment of Myopic Macular Holes: Healing Processes and Morphological Changes in Comparison with Complete ILM Removal.

Maurizio Mete, Alessandro Alfano, Emilia Maggio, Massimo Guerriero, Grazia Pertile

Abstract read
In one paragraph

Article in Journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Delayed closure of highly myopic macular holes combined with retinoschisis after inverted internal limiting membrane flap.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maurizio MeteDepartment of Ophthalmology, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.ORCID 0000-0002-2442-4081
Alessandro AlfanoDepartment of Ophthalmology, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.
Emilia MaggioDepartment of Ophthalmology, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.ORCID 0000-0001-5656-820X
Massimo GuerrieroDepartment of Computer Science, University of Verona, Verona, Italy.
Grazia PertileDepartment of Ophthalmology, Sacro Cuore-Don Calabria Hospital, Negrar, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the microstructural changes after successful myopic macular hole (MMH) surgery, comparing inverted ILM flap and complete ILM removal techniques, and their association with visual function.

methodsSpectral-domain optical coherence tomography (SD-OCT) was used to evaluate both external limiting membrane (ELM) and ellipsoid zone (EZ) recovery in 40 eyes of 39 patients who underwent pars plana vitrectomy with either inverted internal limiting membrane flap technique (

resultsELM and EZ was recovered in 72% and 62% of cases, respectively, regardless of the surgical techniques 1 year after surgery. A strong positive association between the ELM and EZ recovery and the mean BCVA was found: regardless of the surgical technique, this was statistically significant at each time point (

conclusionThe inverted ILM flap technique did not affect the MMH healing processes compared to complete ILM removal. Thus, the presence of the ILM plug did not interfere with the restoration of both ELM and EZ, which correlated with functional recovery.

Identifiers

PMID31275628
PMCPMC6589202

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