Evidence map›Paper›PMID 31275604›Full record

ArticleBMJ open sport & exercise medicine2019

Evaluation of the effect of cooling strategies on recovery after surgical intervention.

Daniel Engelhard, Pierre Hofer, Simon Annaheim

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open sport & exercise medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07416721 (Effects of the Cooling of the Knee After Total Knee Replacement), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07416721 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of the Cooling of the Knee After Total Knee Replacement: Does It Help Compared With a Standard Protocol?

TypeinterventionalSponsorClinical Center of VojvodinaRan2026 to 2027Enrolled99ConditionsOsteoarthritis, Knee, Total Knee ReplacementArmsCool Down Liquid with Bandage ( CoolDown, CH), Ice package cooling system, Standard Postoperative Protocol Without Cooling
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Convection-basedWorld journal of experimental medicine · 2026
    Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daniel EngelhardOrthopädie St. Gallen, St. Gallen, Switzerland.ORCID 0000-0001-9306-0237
Pierre HoferOrthopädie St. Gallen, St. Gallen, Switzerland.
Simon AnnaheimEmpa, Laboratory for Biomimetic Membranes and Textiles, St. Gallen, Switzerland.
University of St.Gallen · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDifferent cooling strategies exist for emergency treatments immediately after sports trauma or after surgery. The aim of this study was to investigate the effects of three cooling regimen during the immediate postoperative phase as well as in the rehabilitation phase.

methods36 patients undergoing anterior cruciate ligament reconstruction received either no cooling (control-group, Con, N=12), were cooled with a menthol-containing cooling bandage (Mtl, N=12) or cooled with an ice containing cold pack (CP, N=12). During a 12-week physiotherapy treatment the cross section of the vastus medialis muscle was examined (day-1; 30; 60; 90) and painkiller consumption was documented.

resultsA significant reduction in the cross section area 30 days after surgery was observed in CP and Con (Mtl: -3.2±1.7%, p=0.14, CP: -8.8±4.3%, p<0.01, Con: -7.2±8.1%, p<0.05). After 90 days of therapy, a significant increase in muscle cross section area was observed in Mtl (Mtl: 4.6%±6.1%, p<0.05, CP: 1.9%± 8.1%, p=0.29, Con: 3.3%±9.4%, p=0.31). The absolute painkiller consumption was lower for Mtl (25.5±3.7 tablets) than for CP (39.5±6.9 tablets) or Con (34.8±4.2 tablets).

conclusionWe observed a beneficial effect of cooling by a menthol-containing bandage during the rehabilitation phase. Reduction of muscle cross section within 30 days after surgery was prevented which highly contributed to rehabilitation success after 90 days of therapy. Painkiller consumption was reduced with Mtl.

Indexed as

orthopaedicsphysiotherapyrecoveryrehabilitationsports medicine

Identifiers

PMID31275604
PMCPMC6579562
OpenAlexW2953160246

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.