ReviewInternational journal of inflammation2019
Skin Acute Wound Healing: A Comprehensive Review.
Review in International journal of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 282 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
282 citing papers in PubMed, 1 synthesis or guideline pooled it, 663 citations in OpenAlex.
- Cytokines and Venous Leg Ulcer Healing-A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Wound healing potential of Sarcophaga aegyptiaca larval excretion/secretion: in vivo assessment of inflammatory biomarkers and in silico molecular docking study.Journal of molecular histology · 2026Article
- A phase field model with stochastic input simulates cellular gradient sensing, morphodynamics, and fidelity of haptotaxis.PLoS computational biology · 2026Article
- Force-responsive biomaterials drive tissue repair by harnessing endogenous growth factors.Nature materials · 2026Article
- Hemostatic and Wound Healing Nonisocyanate Polyhydroxyurethanes (NIPHUs) Dressings from Soybean Oil:ACS omega · 2026Article
- Photobiomodulation therapy and postoperative recovery after abdominoplasty: a non-randomized pilot study.Lasers in medical science · 2026Article
- A perforator-based adipocutaneous skin paddle derived from free muscle flap reconstruction as a hypothesis-generating human tissue model of early localized lymphatic insufficiency.Scientific reports · 2026Article
- Bioactive Hydrogels with D-Amino Acid RGD Mimics: A Therapeutic Strategy for Expeditious Infected Wound Closure.Advanced healthcare materials · 2026Article
- Multifunctional Prussian-Blue-Based Hydrogel for Photothermal Antibacterial and Infected Wound Regeneration.Polymers · 2026Article
- Unveiling and Benefits of Topically Applied l-(+)-Ergothioneine in Periwound Region.International journal of molecular sciences · 2026Article
- Review
- Use of fractional and microablative CO2 laser in cases of vulvar lichen sclerosus: a clinical-histological analysis.Lasers in medical science · 2026Article
- Chitosan-fibrinogen-thrombin matrix accelerates re-epithelialization and cornification in a rat wound healing model.NPJ Regenerative medicine · 2026Article
- Development of Resveratrol/Curcumin Dual-Loaded Chitosan/Sericin Hydrogel Films for Wound Healing: A Comparison Of Shrimp- and Crab-Sourced Chitosan.AAPS PharmSciTech · 2026Article
- Functional Hybrid Wound Scaffolds for Controlled Drug Delivery and Smart Wound Management: A Decade of Progress.AAPS PharmSciTech · 2026Review
- Multifunctional Hydrogel-Based Scaffolds: Integrating Conductive Nanomaterials for Smart Wound Healing Applications.Gels (Basel, Switzerland) · 2026Review
- Review
- A Scallop Active Peptide-Incorporated Carboxymethyl Chitosan/Oxidized Sodium Alginate Hydrogel for Accelerating Skin Wound Healing and Tissue Regeneration.Gels (Basel, Switzerland) · 2026Article
- Effect ofOpen veterinary journal · 2026Article
- Mechanically Induced Skin Renewal: Evidence-Based Insights Into Clinical, Structural and Inflammatory Changes Activated by Microneedling, Microdermabrasion and Microvibration.Journal of cosmetic dermatology · 2026Review
222 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Experimental work of the last two decades has revealed the general steps of the wound healing process. This complex network has been organized in three sequential and overlapping steps. The first step of the inflammatory phase is an immediate response to injury; primary sensory neurons sense injury and send danger signals to the brain, to stop bleeding and start inflammation. The following target of the inflammatory phase, led by the peripheral blood mononuclear cells, is to eliminate the pathogens and clean the wound. Once this is completed, the inflammatory phase is resolved and homeostasis is restored. The aim of the proliferative phase, the second phase, is to repair wound damage and begin tissue remodeling. Fibroplasia, reepithelialization, angiogenesis, and peripheral nerve repair are the central actions of this phase. Lastly, the objective of the final phase is to complete tissue remodeling and restore skin integrity. This review provides present day information regarding the status of the participant cells, extracellular matrix, cytokines, chemokines, and growth factors, as well as their interactions with the microenvironment during the wound healing process.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.