Evidence map›Paper›PMID 31275451›Full record

ArticleDisease markers2019

Glutathione Transferase P1 Polymorphism Might Be a Risk Determinant in Heart Failure.

Dejan Simeunovic, Natalija Odanovic, Marija Pljesa-Ercegovac, Tanja Radic, Slavica Radovanovic, Vesna Coric, Ivan Milinkovic, Marija Matic, Tatjana Djukic, Arsen Ristic and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. An updated analysis on the association ofThe Journal of international medical research · 2022
    Pooled it
  3. Pooled it
  4. Trial
  5. GSTP1 inhibits angiotensin II-induced atrial fibrillation by regulating ferroptosis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
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  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Glutathione S-Transferase P1 Genetic Variant's Influence on the HbA1c Level in Type Two Diabetic Patients.International journal of environmental research and public health · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Dejan SimeunovicClinic of Cardiology, Clinical Center of Serbia, 8 Koste Todorovića, 11000 Belgrade, Serbia.
Natalija OdanovicSection of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Marija Pljesa-ErcegovacFaculty of Medicine, University of Belgrade, 8 Doktora Subotica, 11000 Belgrade, Serbia.
Tanja RadicFaculty of Medicine, University of Belgrade, 8 Doktora Subotica, 11000 Belgrade, Serbia.
Slavica RadovanovicUniversity Clinical Hospital Center "Dr. Dragisa Misovic-Dedinje", Heroja Milana Tepica 1, 11000 Belgrade, Serbia.
Vesna CoricFaculty of Medicine, University of Belgrade, 8 Doktora Subotica, 11000 Belgrade, Serbia.
Ivan MilinkovicClinic of Cardiology, Clinical Center of Serbia, 8 Koste Todorovića, 11000 Belgrade, Serbia.
Marija MaticFaculty of Medicine, University of Belgrade, 8 Doktora Subotica, 11000 Belgrade, Serbia.
Tatjana DjukicFaculty of Medicine, University of Belgrade, 8 Doktora Subotica, 11000 Belgrade, Serbia.
Arsen RisticClinic of Cardiology, Clinical Center of Serbia, 8 Koste Todorovića, 11000 Belgrade, Serbia.
Dijana RisimicFaculty of Medicine, University of Belgrade, 8 Doktora Subotica, 11000 Belgrade, Serbia.
Petar SeferovicClinic of Cardiology, Clinical Center of Serbia, 8 Koste Todorovića, 11000 Belgrade, Serbia.
Tatjana SimicFaculty of Medicine, University of Belgrade, 8 Doktora Subotica, 11000 Belgrade, Serbia.
Dragan SimicClinic of Cardiology, Clinical Center of Serbia, 8 Koste Todorovića, 11000 Belgrade, Serbia.ORCID 0000-0003-4031-3573
Ana Savic-RadojevicFaculty of Medicine, University of Belgrade, 8 Doktora Subotica, 11000 Belgrade, Serbia.ORCID 0000-0002-2026-4180
University of Belgrade · RSUniversity Hospital Center Dr Dragiša Mišović · RSYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disturbed redox balance in heart failure (HF) might contribute to impairment of cardiac function, by oxidative damage, or by regulation of cell signaling. The role of polymorphism in glutathione transferases (

Indexed as

Polymorphism, Single NucleotideAgedCardiomyopathy, DilatedCoronary Artery DiseaseFemaleGlutathione S-Transferase piHeart FailureHumansMaleMiddle AgedGlutathione S-Transferase piGSTP1 protein, human

Identifiers

PMID31275451
PMCPMC6589253
OpenAlexW2947022589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.