Evidence map›Paper›PMID 31275445›Full record

ArticleDisease markers2019

No Association between the rs1799836 Polymorphism of the Monoamine Oxidase B Gene and the Risk of Autism Spectrum Disorders in the Kazakhstani Population.

Anastassiya V Perfilyeva, Kira B Bespalova, Liliya A Skvortsova, Assel Surdeanu, Aleksandr A Garshin, Yuliya V Perfilyeva, Ozada Kh Khamdiyeva, Bakhytzhan O Bekmanov, Leyla B Djansugurova

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  5. Autism and the Knowledge and Beliefs of Specialists in Kazakhstan.Journal of autism and developmental disorders · 2022
    Article
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  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Anastassiya V PerfilyevaInstitute of General Genetics and Cytology CS MES RK, Almaty 050000, Kazakhstan.ORCID 0000-0003-2121-0042
Kira B BespalovaAl-Farabi KazNU, Almaty 050000, Kazakhstan.ORCID 0000-0001-8031-447X
Liliya A SkvortsovaInstitute of General Genetics and Cytology CS MES RK, Almaty 050000, Kazakhstan.ORCID 0000-0002-2035-2244
Assel SurdeanuInstitute of General Genetics and Cytology CS MES RK, Almaty 050000, Kazakhstan.
Aleksandr A GarshinInstitute of General Genetics and Cytology CS MES RK, Almaty 050000, Kazakhstan.ORCID 0000-0003-3922-0783
Yuliya V PerfilyevaM. Aitkozhin Institute of Molecular Biology and Biochemistry, Almaty 050000, Kazakhstan.
Ozada Kh KhamdiyevaInstitute of General Genetics and Cytology CS MES RK, Almaty 050000, Kazakhstan.
Bakhytzhan O BekmanovInstitute of General Genetics and Cytology CS MES RK, Almaty 050000, Kazakhstan.
Leyla B DjansugurovaInstitute of General Genetics and Cytology CS MES RK, Almaty 050000, Kazakhstan.
Al-Farabi Kazakh National University · KZInstitute of Plant Biology and Biotechnology · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorders (ASDs) are heterogeneous diseases that are triggered by a number of environmental and genetic factors. The aim of the current study was to investigate an association of the rs1799836 genetic variant of the neurotransmitter-related gene MAOB with ASDs. In total, 262 patients diagnosed with ASDs and their 126 healthy siblings were included in the present study. All individuals represented a Kazakhstani population. The distributions of the rs1799836 genotype were in accordance with the Hardy-Weinberg equilibrium among both cases and controls. No statistically significant differences were found in the allelic distributions of this polymorphism between ASD and control subjects (A/G: for males OR = 1.11, 95% 0.59-2.06,

Indexed as

Polymorphism, Single NucleotideAdolescentAdultAutism Spectrum DisorderChildChild, PreschoolFemaleHumansKazakhstanMaleMonoamine OxidaseSiblingsMonoamine Oxidase

Identifiers

PMID31275445
PMCPMC6589232
OpenAlexW2947205756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.