Evidence map›Paper›PMID 31275321›Full record

ArticleFrontiers in immunology2019

The Secreted Virulence Factor NADase of Group A

Elsa Westerlund, Christine Valfridsson, Daisy X Yi, Jenny J Persson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Characterization ofFrontiers in microbiology · 2025
    Article
  2. Interplay between group AMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  3. Review
  4. Article
  5. Purinergic Signalling in Group AFrontiers in immunology · 2022
    Article
  6. Playing With Fire: Proinflammatory Virulence Mechanisms of Group AFrontiers in cellular and infection microbiology · 2021
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Elsa WesterlundImmunology Section, Department of Experimental Medical Sciences, Lund University, Lund, Sweden.
Christine ValfridssonImmunology Section, Department of Experimental Medical Sciences, Lund University, Lund, Sweden.
Daisy X YiDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, United States.
Jenny J PerssonImmunology Section, Department of Experimental Medical Sciences, Lund University, Lund, Sweden.
Lund University · SEUniversity of California, Berkeley · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The common human pathogen Group A

Indexed as

AnimalsBacterial ProteinsCell Line, TumorHumansInterleukin-1betaMacrophagesMiceMice, Inbred C57BLMice, KnockoutNAD+ NucleosidaseNLR Family, Pyrin Domain-Containing 3 ProteinReceptors, Purinergic P2X7Streptococcus pyogenesStreptolysinsTHP-1 CellsVirulence FactorsBacterial ProteinsIL1B protein, humanInterleukin-1betaNAD+ NucleosidaseNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanReceptors, Purinergic P2X7streptolysin OStreptolysinsVirulence FactorsGroup A StreptococcusIL-1βmembrane permeabilizationNADaseP2X7

Identifiers

PMID31275321
PMCPMC6591467
OpenAlexW2950773853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.