Evidence map›Paper›PMID 31275139›Full record

ArticleFrontiers in aging neuroscience2019

Effects of tDCS of Dorsolateral Prefrontal Cortex on Dual-Task Performance Involving Manual Dexterity and Cognitive Task in Healthy Older Adults.

Milos R Ljubisavljevic, Joji Oommen, Sasa Filipovic, Jovana Bjekic, Miklos Szolics, Nico Nagelkerke

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Combining transcranial electrical stimulation with training in older adults: Effects on dual-task ability.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
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  17. A Neuro-Computational Model for Discrete-Continuous Dual-Task Process.Frontiers in computational neuroscience · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Milos R LjubisavljevicDepartment of Physiology, College of Medicine and Health Sciences (CMHS), UAE University, Al Ain, United Arab Emirates.
Joji OommenDepartment of Physiology, College of Medicine and Health Sciences (CMHS), UAE University, Al Ain, United Arab Emirates.
Sasa FilipovicDepartment of Neuroscience, Institute for Medical Research, University of Belgrade, Belgrade, Serbia.
Jovana BjekicDepartment of Neuroscience, Institute for Medical Research, University of Belgrade, Belgrade, Serbia.
Miklos SzolicsDepartment of Internal Medicine, Neurology Section, Tawam Hospital, Al Ain, United Arab Emirates.
Nico NagelkerkeInstitute of Public Health, College of Medicine and Health Sciences (CMHS), UAE University, Al Ain, United Arab Emirates.
United Arab Emirates University · AEUniversity of Belgrade · RSTawam Hospital · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Healthy aging limits the activities of daily living and personal independence. Furthermore, cognitive-motor interference in dual-task (e.g., walking while talking) appears to be more pronounced in the elderly. Transcranial direct current stimulation (tDCS), a form of the non-invasive brain stimulation technique, is known to modify cortical excitability and has been investigated as a tool for enhancing motor and cognitive performance in health and disease. The present study examined whether tDCS targeting the dorsolateral prefrontal cortex (DLPFC) could improve dual-task performance in healthy older adults. The effects of tDCS, among other factors, depend on stimulation polarity (anodal vs. cathodal), electrode setup (unilateral vs. bilateral) and the time of application (off-line vs. on-line). We therefore explored the effects of unilateral and simultaneous bilateral tDCS (anodal and cathodal) of left DLPFC while performing (on-line) the Grooved Pegboard Test (GPT) and Serial Seven Subtraction Test (SSST) alone or together (dual-tasking). The number of pegs and the number of correct subtractions were recorded before, during and 30 min after tDCS. The dual-task performance was measured as the percent change from single- to the dual-task condition (dual-task cost DTC). Only bilateral, anode left tDCS, induced a significant increase in subtracted numbers while dual-tasking, i.e., it reduced the DTC of manual dexterity (GPT) to a cognitive task. Significant changes 30 min after the stimulation were only present after bilateral anode right (BAR) tDCS on GPT dual-task costs. These findings suggest that anodal tDCS applied on-line interacts with a dual-task performance involving demanding cognitive and manual dexterity tasks. The results support the potential use of non-invasive brain stimulation for improvement of cognitive functioning in daily activities in older individuals.

Indexed as

agingcognitive taskDLPFCdual-taskingmotor dexterity tasktDCS

Identifiers

PMID31275139
PMCPMC6592113
OpenAlexW2950811933

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.