Evidence map›Paper›PMID 31275120›Full record

ArticleFrontiers in behavioral neuroscience2019

Prophylactic Effects of

Ying Guo, Jian-Ping Xie, Ke Deng, Xia Li, Yun Yuan, Qun Xuan, Jing Xie, Xiao-Ming He, Qian Wang, Juan-Juan Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 5 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 5 syntheses or guidelines pooled it, 121 citations in OpenAlex.

  1. Pooled it
  2. Probiotics for the treatment of depression and its comorbidities: A systemic review.Frontiers in cellular and infection microbiology · 2023
    Pooled it
  3. Pooled it
  4. The microbiota-gut- hippocampus axis.Frontiers in neuroscience · 2022
    Pooled it
  5. Pooled it
  6. Trial
  7. Nutrients · 2024
    Trial
  8. PsychobioticFrontiers in immunology · 2023
    Trial
  9. Article
  10. Review
  11. Review
  12. Journal of microbiology and biotechnology · 2026
    Article
  13. Lanzhou Lily (Food science & nutrition · 2026
    Article
  14. Review
  15. Article
  16. Gut Microbiota-Driven Pathways Linking Chronic Stress to Tumor Progression.International journal of biological sciences · 2026
    Review
  17. Article
  18. Article
  19. Article
  20. Review

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Ying GuoState Key Laboratory of Phytochemistry and Plant Resources in West China, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
Jian-Ping XieLibrary, Yunnan Minzu University, Kunming, China.
Ke DengState Key Laboratory of Phytochemistry and Plant Resources in West China, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
Xia LiSchool of Basic Medical Sciences, Kunming Medical University, Kunming, China.
Yun YuanSchool of Basic Medical Sciences, Kunming Medical University, Kunming, China.
Qun XuanSchool of Basic Medical Sciences, Kunming Medical University, Kunming, China.
Jing XieState Key Laboratory of Phytochemistry and Plant Resources in West China, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
Xiao-Ming HeState Key Laboratory of Phytochemistry and Plant Resources in West China, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
Qian WangSchool of Basic Medical Sciences, Kunming Medical University, Kunming, China.
Juan-Juan LiSchool of Basic Medical Sciences, Kunming Medical University, Kunming, China.
Huai-Rong LuoState Key Laboratory of Phytochemistry and Plant Resources in West China, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.
Kunming Medical University · CNChinese Academy of Sciences · CNMinzu University of China · CNKunming Institute of Botany · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stress disturbs the balance of the gut microbiota and stimulates inflammation-to-brain mechanisms. Moreover, stress leads to anxiety and depressive disorders.

Indexed as

antidepressantBifidobacterium adolescentischronic restraint stressgut microbiotainflammation

Identifiers

PMID31275120
PMCPMC6591489
OpenAlexW2945962757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.