Evidence map›Paper›PMID 31275094›Full record

ArticleFrontiers in neuroscience2019

Non-pulsed Sinusoidal Electromagnetic Field Rescues Animals From Severe Ischemic Stroke via NO Activation.

Lena P Font, Miriam M Cardonne, Hannelore Kemps, Raf Meesen, Oneida F Salmon, Fidel G González, Ivo Lambrichts, Jean-Michel Rigo, Bert Brône, Annelies Bronckaers

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Cellular Mechanisms of Electromagnetic Field in Traumatic Brain Injury.Journal of biotechnology and biomedicine · 2023
    Article
  9. Article
  10. Extremely low frequency electromagnetic stimulation reduces ischemic stroke volume by improving cerebral collateral blood flow.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Lena P FontFaculty of Medicine and Life Sciences, BIOMED, UHasselt - Hasselt University, Diepenbeek, Belgium.
Miriam M CardonneCentro Nacional de Electromagnetismo Aplicado, Universidad de Oriente, Santiago de Cuba, Cuba.
Hannelore KempsFaculty of Medicine and Life Sciences, BIOMED, UHasselt - Hasselt University, Diepenbeek, Belgium.
Raf MeesenFaculty of Medicine and Life Sciences, BIOMED, UHasselt - Hasselt University, Diepenbeek, Belgium.
Oneida F SalmonCentro Nacional de Electromagnetismo Aplicado, Universidad de Oriente, Santiago de Cuba, Cuba.
Fidel G GonzálezCentro Nacional de Electromagnetismo Aplicado, Universidad de Oriente, Santiago de Cuba, Cuba.
Ivo LambrichtsFaculty of Medicine and Life Sciences, BIOMED, UHasselt - Hasselt University, Diepenbeek, Belgium.
Jean-Michel RigoFaculty of Medicine and Life Sciences, BIOMED, UHasselt - Hasselt University, Diepenbeek, Belgium.
Bert BrôneFaculty of Medicine and Life Sciences, BIOMED, UHasselt - Hasselt University, Diepenbeek, Belgium.
Annelies BronckaersFaculty of Medicine and Life Sciences, BIOMED, UHasselt - Hasselt University, Diepenbeek, Belgium.
Hasselt University · BEUniversidad de Oriente · CU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the high prevalence and devastating outcome, only a few treatment options for cerebral ischemic stroke exist. Based on the nitric oxide (NO)-stimulating capacity of Non-pulsed Sinusoidal Electromagnetic Field (NP-SEMF) and the possible neuroprotective role of NO in ischemic stroke, we hypothesized that NP-SEMF is able to enhance survival and neurological outcome in a rat model of cerebral ischemia. The animals, in which ischemic injury was induced by occlusion of both common carotid arteries, received 20 min of NP-SEMF of either 10 or 60 Hz daily for 4 days. NP-SEMF dramatically increased survival, reduced the size of the infarcted brain area and significantly improved the neurological score of the surviving rats. Corresponding to previous reports, NP-SEMF was able to induce NO production

Indexed as

cerebral ischemiaelectromagnetic fieldendothelial cellneuroprotectionnitric oxide

Identifiers

PMID31275094
PMCPMC6593085
OpenAlexW2949392867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.