Evidence map›Paper›PMID 31275082›Full record

ReviewContrast media & molecular imaging2019

MR Imaging-Histology Correlation by Tailored 3D-Printed Slicer in Oncological Assessment.

D Baldi, M Aiello, A Duggento, M Salvatore, C Cavaliere

Abstract readReview
In one paragraph

Review in Contrast media & molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

D BaldiIRCCS SDN, Napoli, Italy.
M AielloIRCCS SDN, Napoli, Italy.ORCID 0000-0002-3676-0664
A DuggentoDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.ORCID 0000-0001-6030-5269
M SalvatoreIRCCS SDN, Napoli, Italy.
C CavaliereIRCCS SDN, Napoli, Italy.ORCID 0000-0002-3297-2213

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

3D printing and reverse engineering are innovative technologies that are revolutionizing scientific research in the health sciences and related clinical practice. Such technologies are able to improve the development of various custom-made medical devices while also lowering design and production costs. Recent advances allow the printing of particularly complex prototypes whose geometry is drawn from precise computer models designed on in vivo imaging data. This review summarizes a new method for histological sample processing (applicable to e.g., the brain, prostate, liver, and renal mass) which employs a personalized mold developed from diagnostic images through computer-aided design software and 3D printing. Through positioning the custom mold in a coherent manner with respect to the organ of interest (as delineated by in vivo imaging data), the cutting instrument can be precisely guided in order to obtain blocks of tissue which correspond with high accuracy to the slices imaged. This approach appeared crucial for validation of new quantitative imaging tools, for an accurate imaging-histopathological correlation and for the assessment of radiogenomic features extracted from oncological lesions. The aim of this review is to define and describe 3D printing technologies which are applicable to oncological assessment and slicer design, highlighting the radiological and pathological perspective as well as recent applications of this approach for the histological validation of and correlation with MR images.

Indexed as

AnimalsComputer-Aided DesignHistological TechniquesHumansImaging, Three-DimensionalMagnetic Resonance ImagingMedical Laboratory SciencePrinting, Three-Dimensional

Identifiers

PMID31275082
PMCPMC6560325

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.