Evidence map›Paper›PMID 31274952›Full record

ArticleThe Canadian journal of statistics = Revue canadienne de statistique2019

A Review of Statistical Methods in Imaging Genetics.

Farouk S Nathoo, Linglong Kong, Hongtu Zhu

Abstract read
In one paragraph

Article in The Canadian journal of statistics = Revue canadienne de statistique, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. aXonica: A support package for MRI based Neuroimaging.Biotechnology notes (Amsterdam, Netherlands) · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Genetic underpinnings of brain structural connectome for young adults.Journal of the American Statistical Association · 2023
    Article
  12. Article
  13. Orthogonalized Kernel Debiased Machine Learning for Multimodal Data Analysis.Journal of the American Statistical Association · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Multivariate Analysis and Modelling of multiple Brain endOphenotypes: Let's MAMBO!Computational and structural biotechnology journal · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Farouk S NathooDepartment of Mathematics and Statistics, University of Victoria.
Linglong KongDepartment of Mathematical and Statistical Sciences, University of Alberta.
Hongtu ZhuDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center.
The University of Texas MD Anderson Cancer Center · USUniversity of Alberta · CAUniversity of Victoria · CA

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Statistical Analysis of Biomedical Imaging Data in Curved SpaceR01MH086633 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI IBRAHIM, JOSEPH G · 2010 to 2018
$2.9M
Genome-wide Identification of Variants Affecting Early Human Brain DevelopmentR01MH092335 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KNICKMEYER, REBECCA · 2011 to 2015
$2.5M
Analysis of Big Data Squared in Biomedical StudiesR01MH116527 · NIMH · YALE UNIVERSITY · PI ZHANG, HEPING · 2018 to 2022
$2.3M
NIA NIH HHS U01 AG024904NIMH NIH HHS R01 MH086633NIMH NIH HHS R01 MH092335NIMH NIH HHS R01 MH116527
6 · The paper itself

Abstract

With the rapid growth of modern technology, many biomedical studies are being conducted to collect massive datasets with volumes of multi-modality imaging, genetic, neurocognitive, and clinical information from increasingly large cohorts. Simultaneously extracting and integrating rich and diverse heterogeneous information in neuroimaging and/or genomics from these big datasets could transform our understanding of how genetic variants impact brain structure and function, cognitive function, and brain-related disease risk across the lifespan. Such understanding is critical for diagnosis, prevention, and treatment of numerous complex brain-related disorders (e.g., schizophrenia and Alzheimer's disease). However, the development of analytical methods for the joint analysis of both high-dimensional imaging phenotypes and high-dimensional genetic data, a big data squared (BD

Indexed as

Group Sparse RegressionMultivariate High-Dimensional RegressionNeuroimaging PhenotypePrimary 62F15Reduced Rank Regression MSC 2010secondary 62G10Single Nucleotide Polymorphism

Identifiers

PMID31274952
PMCPMC6605768
OpenAlexW2915629137

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.