Evidence map›Paper›PMID 31274934›Full record

ArticleSynthesis2019

Palladium-catalyzed coupling reactions on functionalized 2-trifluoromethyl-4-chromenone scaffolds. Synthesis of highly functionalized trifluoromethyl-heterocycles.

Javier Izquierdo, Atul D Jain, Sarki A Abdulkadir, Gary E Schiltz

Abstract read
In one paragraph

Article in Synthesis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Enzymatic synthesis of fluorinated compounds.Applied microbiology and biotechnology · 2021
    Review
  4. Recent Progress Concerning theMolecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Javier IzquierdoCenter for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, Illinois, USA.
Atul D JainCenter for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, Illinois, USA.
Sarki A AbdulkadirDepartment of Urology, Northwestern University, Chicago, Illinois, USA.
Gary E SchiltzCenter for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, Illinois, USA.
Northwestern University · PHRobert H. Lurie Comprehensive Cancer Center of Northwestern University

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
Small molecule CXCR4 modulators as molecular probes for studying AMLR01CA189074 · NCI · NORTHWESTERN UNIVERSITY · PI MILLER, RICHARD J, PLATANIAS, LEONIDAS C. · 2015 to 2017
$1.6M
NCI NIH HHS P30 CA060553NCI NIH HHS R01 CA189074
6 · The paper itself

Abstract

The chromenone core is a ubiquitous group in biologically-active natural products and has been extensively used in organic synthesis. Fluorine derived compounds, including those with a trifluoromethyl group (-CF

Indexed as

chromenoneFluorineheterocycle synthesispalladium-catalyzed couplingtrifluoromethyl-

Identifiers

PMID31274934
PMCPMC6605783
OpenAlexW2901529446

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.