Evidence map›Paper›PMID 31274483›Full record

Observational studyAnnals of cardiac anaesthesia

Chronic postthoracotomy pain in transapical transcatheter aortic valve replacement.

Brian R Gebhardt, Ankit Jain, Sarah A Basaham, Farhad Zahedi, Stefan Ianchulev, Larry H Brinckerhoff, John G Augoustides, Prakash A Patel, Andrea Tsai, Frederick C Cobey

Abstract readObservational Study
In one paragraph

Observational study in Annals of cardiac anaesthesia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Brian R GebhardtDepartment of Anesthesiology, Tufts Medical Center, Boston, MA, USA.
Ankit JainDepartment of Anesthesiology, Tufts Medical Center, Boston, MA, USA.
Sarah A BasahamDepartment of Anesthesiology, Tufts Medical Center, Boston, MA, USA; Department of Anesthesia and Critical Care, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Farhad ZahediDepartment of Anesthesiology, Tufts Medical Center, Boston, MA, USA.
Stefan IanchulevDepartment of Anesthesiology, Tufts Medical Center, Boston, MA, USA.
Larry H BrinckerhoffDepartment of Surgery, Tufts Medical Center, Boston, MA, USA.
John G AugoustidesCardiovascular and Thoracic Section Anesthesiology and Critical Care, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, USA.
Prakash A PatelDepartment of Anesthesiology, University of Pennsylvania, Philadelphia, PA, USA.
Andrea TsaiDepartment of Anesthesiology, Tufts Medical Center, Boston, MA, USA.
Frederick C CobeyDepartment of Anesthesiology, Tufts Medical Center, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Chronic postthoracotomy pain (CPTP) is a persistent, occasionally debilitating pain lasting >2 months following thoracic surgery. This study investigates for the first time the prevalence and clinical impact of CPTP in patients who have undergone a transapical transcatheter aortic valve replacement (TA-TAVR). Design: This was a single-institution, prospective observational survey and a retrospective chart review. Setting: The study was conducted in the University Hospital. Participants: Patients. Materials and Methods: A survey of 131 participants with either a previous TA TAVR or transfemoral (TF) TAVR procedure was completed. A telephone interview was conducted at least 2 months following TAVR; participants were asked to describe their pain using the Short-Form McGill Pain Questionnaire. Measurements and Main Results: Odds ratio (OR) was calculated using the proportions of questionnaire responders reporting "sensory" descriptors in the TA-TAVR versus the TF-TAVR groups. Results were then compared to individual Kansas City Cardiomyopathy Questionnaire (KCCQ12) scores and 5-min walk test (5MWT) distances. A total of 119 participants were reviewed (63 TF, 56 TA). Among TA-TAVR questionnaire responders (n = 16), CPTP was found in 64.3% of participants for an average duration of 20.5-month postprocedure (OR = 10, [confidence interval (CI) 95% 1.91-52.5];P = 0.003). TA-TAVR patients identified with CPTP had significant reductions in 5MWT distances (-2.22 m vs. 0.92 m [P = 0.04]) as well as trend toward significance in negative change of KCCQ12 scores OR = 18.82 (CI 95% 0.85-414.99;P = 0.06) compared to those without CPTP. Conclusions: CPTP occurs in patients undergoing TA-TAVR and is possibly associated with a decline quality of life and overall function.

Indexed as

AgedAged, 80 and overChronic PainFemaleHumansMalePostoperative PainRetrospective StudiesThoracotomyTranscatheter Aortic Valve ReplacementAortic valve replacementchronic painthoracotomytransapical transcatheter aortic valve replacement

Identifiers

PMID31274483
PMCPMC6639875

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.