Evidence map›Paper›PMID 31274482›Full record

ArticleAsian journal of andrology

Histologically proven hepatic steatosis associates with lower testosterone levels in men with obesity.

Frederique Van de Velde, Marlies Bekaert, Anne Hoorens, Anja Geerts, Guy T'Sjoen, Tom Fiers, Jean-Marc Kaufman, Yves Van Nieuwenhove, Bruno Lapauw

Open access · goldAbstract read
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Frederique Van de VeldeDepartment of Endocrinology, Ghent University Hospital, 9000 Ghent, Belgium.
Marlies BekaertDepartment of Endocrinology, Ghent University Hospital, 9000 Ghent, Belgium.
Anne HoorensDepartment of Pathology, Ghent University Hospital, 9000 Ghent, Belgium.
Anja GeertsDepartment of Hepathology, Ghent University Hospital, 9000 Ghent, Belgium.
Guy T'SjoenDepartment of Endocrinology, Ghent University Hospital, 9000 Ghent, Belgium.
Tom FiersDepartment of Clinical Biology, Ghent University Hospital, 9000 Ghent, Belgium.
Jean-Marc KaufmanDepartment of Endocrinology, Ghent University Hospital, 9000 Ghent, Belgium.
Yves Van NieuwenhoveDepartment of Gastro-Intestinal Surgery, Ghent University Hospital, 9000 Ghent, Belgium.
Bruno LapauwDepartment of Endocrinology, Ghent University Hospital, 9000 Ghent, Belgium.
Ghent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Men with obesity often present with low testosterone (T) and sex hormone-binding globulin (SHBG) levels. Several mechanisms for this have been proposed, but as SHBG is secreted by hepatocytes and sex steroids undergo hepatic metabolization, this study investigates whether severity and histological components of nonalcoholic fatty liver disease (NAFLD) are associated with sex steroid levels in obese men. This cross-sectional study included 80 obese men (age: 46 ± 11 years; body mass index: 42.2 ± 5.5 kg m

Indexed as

AdultEstradiolFollicle Stimulating HormoneHumansLiver CirrhosisLuteinizing HormoneMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseObesitySeverity of Illness IndexTestosteroneEstradiolFollicle Stimulating HormoneLuteinizing HormoneTestosteronemale hypogonadismnonalcoholic fatty liver diseaseobesitysex steroidssteatosistestosterone

Identifiers

PMID31274482
PMCPMC7275796
OpenAlexW2955690243

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.