Evidence map›Paper›PMID 31274417›Full record

ArticleJournal of synchrotron radiation2019

Shining light on cysteine modification: connecting protein conformational dynamics to catalysis and regulation.

Henry van den Bedem, Mark A Wilson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of synchrotron radiation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Other Techniques.Advances in biochemical engineering/biotechnology · 2026
    Review
  4. Article
  5. Article
  6. Post-translational modifications in the Protein Data Bank.Acta crystallographica. Section D, Structural biology · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Henry van den BedemBioscience Division, SLAC National Accelerator Laboratory, Stanford University, 2575 Sand Hill Road, Menlo Park, CA 94025, USA.ORCID 0000-0003-2358-841X
Mark A WilsonDepartment of Biochemistry and the Redox Biology Center, University of Nebraska, Lincoln, NE 68588, USA.
University of California, San Francisco · USUniversity of Nebraska–Lincoln · US

Funding

Supplement to Resolving ensemble averaged conformations by multi-temperature x-ray crystallography - Equipment 2020R01GM123159 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FRASER, JAMES SOLOMON · 2018 to 2021
$2.3M
NIGMS NIH HHS GM123159NIGMS NIH HHS R01 GM123159
6 · The paper itself

Abstract

Cysteine is a rare but functionally important amino acid that is often subject to covalent modification. Cysteine oxidation plays an important role in many human disease processes, and basal levels of cysteine oxidation are required for proper cellular function. Because reactive cysteine residues are typically ionized to the thiolate anion (Cys-S

Indexed as

CatalysisCrystallography, X-RayCysteineMolecular Dynamics SimulationOxidation-ReductionProtein ConformationProteinsReproducibility of ResultsX-RaysCysteineProteinscysteine modificationenzyme conformational dynamicsmolecular dynamics simulationsradiation-controlled photo-oxidationserial X-ray crystallography

Identifiers

PMID31274417
PMCPMC6613112
OpenAlexW2952770773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.