ArticleAmerican journal of epidemiology2019
The Effects of Reverse Causality and Selective Attrition on the Relationship Between Body Mass Index and Mortality in Postmenopausal Women.
Article in American journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Sex and age influence the association between insulin resistance and all-cause mortality in rheumatoid arthritis patients.Clinical rheumatology · 2026Article
- The Risk of Very Late-Onset Schizophrenia Following Diabetes Type 2 Onset: A Nationwide Population-Based Study of Midlife and Old-Age.Schizophrenia bulletin · 2026Article
- Effect Modification by Cofactors in the Impact of Body Mass Index Change on the Risk of Lung Cancer.Cancer science · 2026Article
- Impact of Annual Dry Weight Changes on Mortality and Cardiovascular Outcomes in Patients Undergoing Haemodialysis.Journal of cachexia, sarcopenia and muscle · 2025Article
- Decomposing the association of psychosocial wellbeing with all-cause mortality: the mediating role of physical health and lifestyle factors.Social psychiatry and psychiatric epidemiology · 2025Article
- Intentional Weight Loss, Waist Circumference Reduction, and Mortality Risk Among Postmenopausal Women.JAMA network open · 2025Observational
- Unveiling Statins and Genetics in Age-Related Macular Degeneration Progression: What Is the Appropriate Modeling Strategy?Investigative ophthalmology & visual science · 2025Article
- Commentary: Added sugar intake and its associations with incidence of seven different cardiovascular diseases in 69,705 Swedish men and women.Frontiers in public health · 2025Article
- [Numerical expression of the clinical course of the disease. Data management].Revista medica del Instituto Mexicano del Seguro Social · 2023Article
- Premorbid weight in pulmonary arterial hypertension.Pulmonary circulation · 2023Article
- Increased risk of colon cancer after acute appendicitis: a nationwide, population-based study.EClinicalMedicine · 2023Article
- Immunomodulatory Effects of Vitamin D in Respiratory Tract Infections and COVID-19 in Children.Nutrients · 2023Review
- Body mass index and all-cause mortality in a 21st century U.S. population: A National Health Interview Survey analysis.PloS one · 2023Article
- An Update on the Epidemiology, Molecular Characterization, Diagnosis, and Screening Strategies for Early-Onset Colorectal Cancer.Gastroenterology · 2021Review
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13 authors.
Funding
Abstract
Concerns about reverse causality and selection bias complicate the interpretation of studies of body mass index (BMI, calculated as weight (kg)/height (m)2) and mortality in older adults. The objective of this study was to investigate methodological explanations for the apparent attenuation of obesity-related risks in older adults. We used data from 68,132 participants in the Women's Health Initiative (WHI) clinical trial for this analysis. All of the participants were postmenopausal women aged 50-79 years at baseline (1993-1998). To examine reverse causality and selective attrition, we compared rate ratios from inverse probability of treatment- and censoring-weighted Poisson marginal structural models with results from an unweighted adjusted Poisson regression model. The estimated mortality rate ratios and 95% confidence intervals for BMIs of 30.0-34.9, 35.0-39.9 and ≥40.0 were 0.86 (95% confidence interval (CI): 0.77, 0.96), 0.85 (95% CI: 0.72, 0.99), and 0.88 (95% CI: 0.72, 1.07), respectively, in the unweighted model. The corresponding mortality rate ratios were 0.96 (95% CI: 0.86, 1.07), 1.12 (95% CI: 0.97, 1.29), and 1.31 95% CI: (1.08, 1.57), respectively, in the marginal structural model. Results from the inverse probability of treatment- and censoring-weighted marginal structural model were attenuated in low BMI categories and increased in high BMI categories. The results demonstrate the importance of accounting for reverse causality and selective attrition in studies of older adults.
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