Evidence map›Paper›PMID 31273901›Full record

ReviewGenes to cells : devoted to molecular & cellular mechanisms2019

A role for epigenetic adaption in evolution.

Ichiro Yahara

Abstract readReview
In one paragraph

Review in Genes to cells : devoted to molecular & cellular mechanisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A role for epigenetic adaption in evolution.Genes to cells : devoted to molecular & cellular mechanisms · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ichiro YaharaTokyo Metropolitan Institute of Medical Science, Tokyo, Japan.ORCID https://orcid.org/0000-0002-5863-5768

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outcome of epigenetic responses to stress depends strictly on genetic background, suggesting that altered phenotypes, when induced, are created by a combination of induced epigenetic factors and pre-existing allelic ones. When individuals with altered phenotypes are selected and subjected to successive breeding, alleles that potentiate epigenetic responses could accumulate in offspring populations. It is reasonable to suppose that many, if not all, of these allelic genes could also be involved in creating new phenotypes under nonstressful conditions. In this review, I discuss the possibility that the accumulation of such alleles in selected individuals with an epigenetic phenotype could give rise to individuals that exhibit the same phenotype even in the absence of stress.

Indexed as

Biological EvolutionEpigenesis, GeneticAdaptation, BiologicalAllelesAnimalsChromatinHSP90 Heat-Shock ProteinsHumansInheritance PatternsModels, GeneticMutationPhenotypeSelection, GeneticStress, PhysiologicalChromatinHSP90 Heat-Shock Proteinsgenetic assimilationHsp90phenotype selectionstress response

Identifiers

PMID31273901
PMCPMC6852114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.