Evidence map›Paper›PMID 31273806›Full record

ArticleVox sanguinis2019

When are infection risks of blood transfusion tolerable? Towards understanding the ethical views of stakeholders in the blood supply.

Koen Kramer, Marcel F Verweij, Hans L Zaaijer

Abstract read
In one paragraph

Article in Vox sanguinis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Koen KramerDepartment of Blood-borne Infections (BOI), Sanquin Blood Supply Foundation, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-7135-6691
Marcel F VerweijDepartment of Communication, Philosophy and Technology (CPT), Wageningen University and Research, Wageningen, The Netherlands.ORCID https://orcid.org/0000-0001-9169-1852
Hans L ZaaijerDepartment of Blood-borne Infections (BOI), Sanquin Blood Supply Foundation, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0003-0773-7315

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe perception of transfusion-transmitted infections (TTIs) is sensitive to various concerns besides the probability and impact of infection, and some of these concerns may be ethically relevant. This paper aims to advance thinking about blood safety policies by exploring and explaining stakeholders' reasons to consider TTI risks tolerable or intolerable. MATERIALS AND

methodsInspired by critical empirical ethics and phenomenological hermeneutics, we held interviews and focus group discussions to explore the moral experience of policymakers, hematologists, blood donors and recipients. Respondents were invited to discuss general concerns about the blood supply, to address the tolerability of TTI risks compared with other hazards and to comment on the costs of blood safety. Arguments for tolerance or intolerance towards TTI risks were analysed qualitatively.

resultsStakeholders' views could be clustered into seven categories: (1) clinical impact; (2) probability of infection; (3) avoidability of infection; (4) cost and health benefits; (5) other consequences of safety measures; (6) non-consequentialist ethical arguments; and (7) stakeholders' interests. Various arguments were offered that resonate with current ethical thinking about blood safety. Assuming that resources spent on inefficient blood safety measures could be applied more beneficially elsewhere, for example, responders typically expressed tolerance towards TTI risks. Some other arguments seem novel, for instance arguments for risk intolerance based on the low probability of infection and arguments for risk tolerance if patients have a poor prognosis.

conclusionUnderstanding the moral experience of stakeholders enriches ethical debate about blood safety and prepares developing more widely acceptable policies.

Indexed as

AdultAgedBlood DonorsBlood SafetyBlood TransfusionFemaleHumansMaleMiddle AgedTransfusion Reactionacceptabilityblood donationblood donorblood recipientrisktransfusion-transmitted infection

Identifiers

PMID31273806
PMCPMC6851576

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