ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2019
Establishing a donor stool bank for faecal microbiota transplantation: methods and feasibility.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Re-establishing bile acid composition after treatment of recurrentGut microbes · 2026Trial
- Impact of a single fecal microbiome transplantation in adult women with anorexia nervosa: an open-label feasibility pilot trial.Nature communications · 2026Article
- Review
- The Role of Fecal Microbiota Transplantation (FMT) in the Management of Metabolic Diseases in Humans: A Narrative Review.Biomedicines · 2024Review
- Fecal microbiota transplantation: current challenges and future landscapes.Clinical microbiology reviews · 2024Review
- Faecal Microbiota Transplantation, Paving the Way to Treat Non-Alcoholic Fatty Liver Disease.International journal of molecular sciences · 2023Review
- Therapy Used to Promote Disease Remission Targeting Gut Dysbiosis, in UC Patients with Active Disease.Journal of clinical medicine · 2022Review
- The Efficacy of Faecal Microbiota Transplant and Rectal Bacteriotherapy in Patients with RecurrentCells · 2022Article
- Adverse events of intestinal microbiota transplantation in randomized controlled trials: a systematic review and meta-analysis.Gut pathogens · 2022Review
- Clinical Practice Guidelines for Fecal Microbiota Transplantation in Korea.Journal of neurogastroenterology and motility · 2022Review
- Long-Term Safety Following Faecal Microbiota Transplantation as a Treatment for RecurrentCells · 2022Review
- The use of Faecal Microbiota Transplantation (FMT) in Europe: A Europe-wide survey.The Lancet regional health. Europe · 2021Article
- Laboratory Aspects of Donor Screening for Fecal Microbiota Transplantation at a Korean Fecal Microbiota Bank.Annals of laboratory medicine · 2021Article
- Faecal microbiota transplantation forUnited European gastroenterology journal · 2020Observational
- Regulation, risk and safety of Faecal Microbiota Transplant.Infection prevention in practice · 2020Review
- Determinants of community members' willingness to donate stool for faecal microbiota transplantation.PloS one · 2020Article
- Economic and Chronologic Optimization of Fecal Donors Screening Process.MDM policy & practiceArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Faecal microbiota transplantation (FMT) is a promising treatment, but donor selection and implementation in clinical practice are difficult. Here, we describe the establishment of a donor stool bank based on the Tissue Act. Stool donors were recruited among blood donors and asked to donate five times in a month. A screening questionnaire, a medical interview and testing of blood and stool were conducted before and after donations. Donations were made at home and transported to the lab, where 50 g of stool was suspended and filtered in saline and 20-mL glycerol (final concentration of 10%) to a volume of 170 mL. The processed stool was assigned a batch number, frozen within 2 h after defecation and stored at - 80 °C for up to 1 year. All steps were documented and cross-checked before donor stool were released for clinical use. Thirteen donors were eligible at the first interview and started donations. Two donors were excluded due to a positive Helicobacter pylori test, two withdrew consent and one was lost to follow-up. One donor took a single dose of NSAIDs 2 days prior to a donation, which was discarded. There were no other excluding findings at the second interview or testing. Eight of the 13 donors were approved as stool donors. All donated five times with each donation yielding 1-6 portions. Eighty-four portions were released for clinical use. Recruiting stool donors among blood donors is safe and effective. The Tissue Act yields an appropriate regulative framework for FMT.
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Registered trials
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