ArticleClinical rheumatology2019
Coronary involvement in patients with Behçet's disease.
Article in Clinical rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Giant Coronary Aneurysm Complicating Behçet's Disease.JACC. Case reports · 2025Article
- Cardiac Manifestations in Behçet's Syndrome.Current rheumatology reports · 2025Review
- Acute Cardiogenic Shock Secondary to Left Main Occlusion in a Patient with Behçet Disease.JACC. Case reports · 2025Article
- Clinical characteristics of coronary artery involvement in children with Behcet's syndrome.Clinical rheumatology · 2025Article
- The association between grade of coronary heart disease and risk of developing keratopathy: a nationwide cohort study.International journal of medical sciences · 2025Article
- Article
- Recurrent left main stem stenosis in a young female with Behçet's aortitis: a case report.European heart journal. Case reports · 2024Article
- The Degrees of Coronary Heart Disease and the Degrees of New-Onset Blepharitis: A Nationwide Cohort Study.Diagnostics (Basel, Switzerland) · 2024Article
- The Extents of Coronary Heart Disease and the Severity of Newly Developed Dry Eye Disease: A Nationwide Cohort Study.Diagnostics (Basel, Switzerland) · 2024Article
- Vascular Involvement in Behcet's Disease: An Evaluation of 147 Cases and Literature Review.Sisli Etfal Hastanesi tip bulteni · 2023Article
- Case report and analysis: Behçet's disease with lower extremity vein thrombosis and pseudoaneurysm.Frontiers in immunology · 2022Article
- Characteristics and phenotype heterogeneity in late-onset Behçet's syndrome: a cohort from a referral center in China.Clinical rheumatology · 2021Article
- Cluster analysis of phenotypes of patients with Behçet's syndrome: a large cohort study from a referral center in China.Arthritis research & therapy · 2021Article
- Uveitis as a potential predictor of acute myocardial infarction in patients with Behcet's disease: a population-based cohort study.BMJ open · 2021Article
- Behçet's Syndrome Apart From the Triple Symptom Complex: Vascular, Neurologic, Gastrointestinal, and Musculoskeletal Manifestations. A Mini Review.Frontiers in medicine · 2021Review
- Cardiovascular Manifestations of Systemic Vasculitides.Current rheumatology reports · 2020Review
- Premature coronary disease, in-stent restenosis and vascular complications in a young man with Behçet syndrome.BMJ case reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo investigate the clinical features and potential risk factors of coronary involvement in Behçet's disease (BD).
methodIn this case-control study, we retrospectively reviewed medical records of BD patients admitted to our institute from 2000 to 2016. Coronary involvement was documented by coronary angiography and (or) computed tomography angiography. We analyzed the demographic, clinical, and laboratory data and compared with age- and gender-matched BD patients without coronary involvement.
resultsAmong 476 BD patients (296 males) enrolled, 19 (4.0%) patients (17 males) were diagnosed with coronary involvement. The median duration from onset of BD to coronary involvement was 2.8 years. Coronary stenosis, aneurysm, and occlusion were presented in 13, 9, and 3 patients, respectively. Multiple coronary artery stenoses and aneurysms were observed in 9 and 3 patients, respectively. Smoking (36.8%) was the major traditional risk factors. Male gender (89.5% vs 61.1%, p = 0.01), skin lesions (78.9% vs 55.3%, p = 0.08), pathergy reactions (36.8% vs 10.5%, p = 0.01), extra-cardiac vasculitis (36.8% vs 6.6% p < 0.01), elevated ESR (57.9% vs 34.2%, p = 0.01), and elevated CRP (63.2% vs 42.1%, p < 0.01) were more common in BD patients with coronary involvement comparing with those without coronary involvement. Multivariate analysis confirmed pathergy reaction (OR = 3.81, 95% CI 1.08-13.47) was the independent risk factor.
conclusionsCoronary involvement in BD patients is rare and male-predominant and is characterized by the aneurysm and multivessel involvement. Elevated ESR and CRP are frequent, and the pathergy reaction is the independent risk factor. Key Points • Coronary involvement in BD patients is rare and male-predominant. • Pathergy reaction is the risk factor for coronary involvement in BD patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.