Evidence map›Paper›PMID 31273593›Full record

ArticleDigestive diseases and sciences2019

Climbing New Mountains: How Antibodies Blocking α4β7 Integrins Tamed Eosinophilic Inflammation of the Intestinal Tract.

Courtney L Olbrich, Luke Simerly, Edwin F de Zoeten, Glenn T Furuta, Lisa A Spencer

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Eosinophilic Gastritis/Gastroenteritis.Current gastroenterology reports · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Courtney L OlbrichDepartment of Pediatrics, Gastrointestinal Eosinophilic Diseases Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine, 12700 East 19th Avenue, Research 2 P15-6026 Mail Stop: C-226, Aurora, CO, 80045, USA.
Luke SimerlyDepartment of Pediatrics, Gastrointestinal Eosinophilic Diseases Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine, 12700 East 19th Avenue, Research 2 P15-6026 Mail Stop: C-226, Aurora, CO, 80045, USA.
Edwin F de ZoetenDepartment of Pediatrics, Gastrointestinal Eosinophilic Diseases Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine, 12700 East 19th Avenue, Research 2 P15-6026 Mail Stop: C-226, Aurora, CO, 80045, USA.
Glenn T FurutaDepartment of Pediatrics, Gastrointestinal Eosinophilic Diseases Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine, 12700 East 19th Avenue, Research 2 P15-6026 Mail Stop: C-226, Aurora, CO, 80045, USA.
Lisa A SpencerDepartment of Pediatrics, Gastrointestinal Eosinophilic Diseases Program, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine, 12700 East 19th Avenue, Research 2 P15-6026 Mail Stop: C-226, Aurora, CO, 80045, USA. Lisa.Spencer@ucdenver.edu.

Funding

TRAINING (CAREER DEVELOPMENT) COMPONENTU54AI117804 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI Marc E. Rothenberg · 2014 to 2026
$18.5M
Eosinophil functions in allergic gastrointestinal diseasesR01AI121186 · NIAID · UNIVERSITY OF COLORADO DENVER · PI SPENCER, LISA ANN · 2017 to 2021
$2.0M
Patient research in eosinophilic gastrointestinal diseasesK24DK100303 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI FURUTA, GLENN T · 2013 to 2017
$889k
NIAID NIH HHS R01 AI121186NIAID NIH HHS U54 AI117804NIDDK NIH HHS K24 DK100303
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adrenal Cortex HormonesIntegrinsAntibodies, Monoclonal, HumanizedEnteritisEosinophiliaGastritisHumansInflammationAdrenal Cortex HormonesAntibodies, Monoclonal, HumanizedIntegrinsvedolizumab

Identifiers

PMID31273593
PMCPMC6946547

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.