ArticleLa Radiologia medica2019
Identification of bone marrow edema of the ankle: diagnostic accuracy of dual-energy CT in comparison with MRI.
Article in La Radiologia medica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Diagnostic accuracy of dual-energy CT for the detection of bone marrow edema in the appendicular skeleton: a systematic review and meta-analysis.European radiology · 2021Pooled it
- Dual-Energy Computed Tomography for the Detection of Bone Edema-Like Lesions in the Equine Foot: Standing Horses and Cadaveric Specimens.Veterinary sciences · 2025Article
- Assessment of bone marrow edema on dual-energy CT scans in people with diabetes mellitus and suspected Charcot neuro-osteoarthropathy.Skeletal radiology · 2025Article
- Identification of Achille's Tendon Tears: Diagnostic Accuracy of Dual-Energy CT with Respect to MRI.Journal of clinical medicine · 2024Article
- Dual-Energy CT in Oncologic Imaging.Tomography (Ann Arbor, Mich.) · 2024Review
- Dual-energy CT: Impact of detecting bone marrow oedema in occult trauma in the Emergency.BJR open · 2024Review
- Preliminary evaluation of dual-energy CT to quantitatively assess bone marrow edema in patients with diabetic foot ulcers and suspected osteomyelitis.European radiology · 2023Article
- Dual-energy CT virtual non-calcium: an accurate method for detection of knee osteoarthritis-related edema-like marrow signal intensity.Insights into imaging · 2023Article
- Osteomyelitis of the Lower Limb: Diagnostic Accuracy of Dual-Energy CT versus MRI.Diagnostics (Basel, Switzerland) · 2023Article
- Ankle Sprains in Athletes: Current Epidemiological, Clinical and Imaging Trends.Open access journal of sports medicine · 2023Review
- DECT Numbers in Upper Abdominal Organs for Differential Diagnosis: A Feasibility Study.Tomography (Ann Arbor, Mich.) · 2022Article
- Virtual non-calcium dual-energy CT: clinical applications.European radiology experimental · 2021Review
- Identification of Traumatic Bone Marrow Oedema: The Pearls and Pitfalls of Dual-Energy CT (DECT).Tomography (Ann Arbor, Mich.) · 2021Article
- Identification of Non-Traumatic Bone Marrow Oedema: The Pearls and Pitfalls of Dual-Energy CT (DECT).Tomography (Ann Arbor, Mich.) · 2021Article
- T2-mapping MRI evaluation of patellofemoral cartilage in patients submitted to intra-articular platelet-rich plasma (PRP) injections.La Radiologia medica · 2021Article
- Plantar forefoot pain: ultrasound findings before and after treatment with custom-made foot orthoses.La Radiologia medica · 2021Article
- Identification of bone marrow edema of the knee: diagnostic accuracy of dual-energy CT in comparison with MRI.La Radiologia medica · 2021Article
- Impact of Magnetic Resonance Imaging (MRI) Findings on Management of Symptomatic Patients Following Radiofrequency Ablation (RFA) of Osteoid Osteoma (OO).SN comprehensive clinical medicine · 2020Article
- Bone marrow edema around the hip in non-traumatic pain: dual-energy CT vs MRI.European radiology · 2020Article
- Edema Surrounding Benign Tumors and Tumor-Like Lesions.BioMed research international · 2019Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the diagnostic accuracy of dual-energy computed tomography (DECT) to identify bone marrow edema (BME) of the ankle.
methodsThis prospective institutional review board approved study included 40 consecutive patients (29 males and 11 females; mean age of 32.3 years) studied with DECT (80 kV and tin filter 150 kV) and MRI within 10 days. DECT data were post-processed for generating non-calcium images of the ankle. Two radiologists evaluated the presence of BME on color-coded maps. Diagnostic accuracy values for diagnosing BME were calculated for DECT maps (qualitative assessment) and for CT numbers (quantitative assessment) by using receiver operator curves and area under the curve (AUC), using MRI as the gold standard. Interobserver and intraobserver agreements were calculated with k-statistics. A p < 0.05 was considered statistically significant.
resultsDECT depicted BME in 23/25 patients (92.0%). The sensitivity, specificity, PPV and NPV, and accuracy achieved by evaluating the DECT images were 92.0, 86.6, 92.0, 84.6, and 90.0%, for reader 1 and 88.0, 86.6, 91.6, 78.6, and 87.5, for reader 2, respectively. The interobserver and intraobsever agreements were near perfect (k = 0.87 and k = 0.83, respectively). DECT numbers were significantly different between positive (mean - 12.6 ± 29.6 HU) and negative cases (mean - 64.2 ± 34.5 HU) with a p value < 0.001. By using - 20HU cutoff to identify BME (AUC of 0.896.), the sensitivity, specificity, PPV and NPV, and accuracy of the quantitative analysis were 88.0, 92.6, 95.7, 92.6, and 87.5%, respectively.
conclusionDECT represents an accurate imaging tool for demonstration of BME of the ankle when compared to MRI.
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