ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020
The role of ICP overnight monitoring (ONM) in children with suspected craniostenosis.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Methodological determinants and prevalence of elevated intracranial pressure in isolated single-suture craniosynostosis: a systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Pooled it
- Sleep, cerebrospinal fluid, and the glymphatic system: A systematic review.Sleep medicine reviews · 2022Pooled it
- Long-term results of minimally invasive strip craniectomy without helmet therapy for scaphocephaly - a single-centre experience.Neurosurgical review · 2024Article
- Transorbital point-of-care ultrasound versus fundoscopic papilledema to support treatment indication for potentially elevated intracranial pressure in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- A clinical evaluation of variation in paediatric intracranial pressure waveforms.Brain & spine · 2024Article
- Frontal sinus hypoplasia in unoperated older patients with craniosynostosis: a pilot study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Transcranial optical monitoring for detecting intracranial pressure alterations in children with benign external hydrocephalus: a proof-of-concept study.Neurophotonics · 2022Article
- The use of OCT to detect signs of intracranial hypertension in patients with sagittal suture synostosis: Reference values and correlations.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Intracranial pressure monitoring in craniosynostosis.Journal of neurosciences in rural practiceArticle
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Authors and funding
6 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
purposeSecondary craniostenosis is a relevant problem pediatric neurosurgeons are confronted with and poses challenges regarding reliable diagnosis of raised ICP, especially in case of absent or questionable papilledema. How to identify children with elevated ICP is still controversial and diagnostics vary. We report on our experience with computerized ICP ONM in relation to imaging derived parameters.
methodsThirty-four children with primary or secondary craniostenosis and clinical suspicion of raised ICP were investigated. We compared clinical signs, history, and radiographic assessment with the results of computerized ICP ONM. Differences were significant at a p < 0.05.
resultsBaseline ICP was significantly higher in patients with combined suture synostosis, who also had a higher rate of questionable papilledema. Children with narrowed external CSF spaces in MRI had significantly higher ICP levels during REM sleep. Mean RAP was significantly elevated in patients with multi-suture synostosis, indicating poor intracranial compensatory reserve. Syndromal craniostenosis was associated with elevated ICP, RAP was significantly lower, and skull X-rays showed more impressions (copper beaten skull). RAP increased with more severe impressions only to decline in most severe abnormalities, indicating exhaustion of cerebrovascular reserve at an upper ICP breakpoint of 23.9 mmHg. Headaches correlated to lower ICP and were not associated with more severe X-ray abnormalities.
conclusionNarrowed external CSF spaces in MRI seem to be associated to elevated ICP. Skull X-rays can help to identify patients at risk for chronically elevated ICP. Severe X-ray changes correlate with exhausted cerebrovascular reserve as indicated by RAP decline. Only ICP monitoring clearly identifies raised ICP and low brain compliance. Thus, in cases with ambiguous imaging, ONM constitutes an effective tool to acquire objective data for identification of surgical candidates.
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