Evidence map›Paper›PMID 31273489›Full record

ArticleAIDS and behavior2019

A Dyadic Investigation of Relationship Dynamics and Depressive Symptoms in HIV-Affected Couples in Malawi.

Emily L Tuthill, Torsten B Neilands, Mallory O Johnson, John Sauceda, James Mkandawire, Amy A Conroy

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06659315 (Addressing Perinatal Depression and PMTCT Adherence in Malawi), which is not on this map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06659315 narecruitingnot on this mapstarted 2025, after this paper: background citation

Addressing Perinatal Depression and PMTCT Adherence in Malawi: A Couple-Based Approach

TypeinterventionalSponsorUniversity of California, San FranciscoRan2025 to 2027Enrolled180ConditionsHIV Antiretroviral Therapy (ART) Adherence, Perinatal Mental Health, Depression During Pregnancy, PMTCTArmsCouples Problem Solving Therapy
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  7. Delineating the dyadic coping process in HIV serodiscordant male couples: a dyadic daily diary study using the common fate model.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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  8. Relationship Dynamics and Young Women's Contraceptive Use.Sexuality research & social policy : journal of NSRC : SR & SP · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emily L TuthillDepartment of Community Health Systems, School of Nursing, University of California, San Francisco, CA, USA. emily.tuthill@ucsf.edu.ORCID http://orcid.org/0000-0001-6729-4101
Torsten B NeilandsDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, University of California San Francisco, San Francisco, CA, USA.
Mallory O JohnsonDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, University of California San Francisco, San Francisco, CA, USA.
John SaucedaDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, University of California San Francisco, San Francisco, CA, USA.
James MkandawireInvest in Knowledge, Zomba, Malawi.
Amy A ConroyDivision of Prevention Sciences, Department of Medicine, Center for AIDS Prevention Studies, University of California San Francisco, San Francisco, CA, USA.
University of California, San Francisco · US

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
TRAINEESHIPS IN AIDS PREVENTION STUDIEST32MH019105 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Carol Suzanne Camlin, Glenn-Milo Santos · 1989 to 2026
$15.3M
Malawi HIV Implementation Research Scientist Training Program (MHIRST)D43TW010060 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MINA CHRISTINE HOSSEINIPOUR, Victor Mwapasa · 2015 to 2026
$3.8M
Understanding the role of food insecurity and depression in non-adherence to Option B+ among perinatal Kenyan women living with HIV: a Syndemics approach supplementK23MH116807 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TUTHILL, EMILY · 2018 to 2022
$1.0M
Mentoring and Empowerment in the Context of HIV Care for At-Risk PopulationsK24DA037034 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, MALLORY O · 2014 to 2018
$918k
An adaptive treatment intervention for depression and engagement in HIV care among Latinos living with HIVK01MH113475 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SAUCEDA, JOHN ANDREW · 2017 to 2020
$787k
Development of a Couple-Based Mobile Health Intervention for Enhancing HIV Care Engagement OutcomesK01MH106416 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TAN, JUDY YOU RONG · 2015 to 2018
$777k
Relationship Factors and Engagement in HIV Care in Malawi: A Dyadic InvestigationK01MH107331 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CONROY, AMY ANNE · 2016 to 2019
$773k
FIC NIH HHS D43 TW010060NIDA NIH HHS K24 DA037034NIH HHS K01MH107331NIH HHS K23MH116807NIH HHS K24DA037034NIMH NIH HHS K01 MH106416NIMH NIH HHS K01 MH107331NIMH NIH HHS K01 MH113475NIMH NIH HHS K23 MH116807NIMH NIH HHS P30 MH062246NIMH NIH HHS T32 MH019105
6 · The paper itself

Abstract

Depression is the leading cause of disability worldwide with health implications for people living with HIV. Primary partnerships like marriage could be protective against depression but may worsen depression depending on the relationship quality. We examined depression and its association with relationship dynamics in a cross-sectional sample of 211 HIV-affected married couples in Malawi. We fit multivariable multilevel linear regression models for depressive symptoms. Men and women reported similar levels of depressive symptoms; 28% had a score indicative of probable depression. Almost half of couples had at least one partner with probable depression. In the adjusted models, equality (B = - 0.22; p < 0.01) and unity (B = - 0.94; p < 0.05) were associated with fewer depressive symptoms while individuals with more experiences of physical (B = 0.81; p < 0.01), sexual (B = 0.87; p < 0.01), and emotional violence (B = 1.52; p < 0.001) had higher levels of depressive symptoms. Couples-based interventions aiming to improve relationships may address depression, especially in settings with inadequate mental health services.

Indexed as

Interpersonal RelationsAdultCross-Sectional StudiesDepressionFemaleHIV InfectionsHumansMalawiMaleMarriageMiddle AgedSexual BehaviorSexual PartnersSpouse AbuseSpousesDepressionHeterosexual couplesHIVRelationship dynamicsSub-Saharan Africa

Identifiers

PMID31273489
PMCPMC6854284
OpenAlexW2954716900

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.