Evidence map›Paper›PMID 31273450›Full record

SynthesisInternational journal of colorectal disease2019

Ambulatory versus conventional laparoscopic appendectomy: a systematic review and meta-analysis.

Mario Trejo-Avila, Eduardo Cárdenas-Lailson, Carlos Valenzuela-Salazar, Jose Herrera-Esquivel, Mucio Moreno-Portillo

3 registry-linked trialsAbstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International journal of colorectal disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04464382 naunknown statusnot on this map

A Randomized Double-blind Clinical Trial to Evaluate the Safety and Efficacy of a Outpatient Appendectomy (PENDI_CSI)

TypeinterventionalSponsorFundación Pública Andaluza para la gestión de la Investigación en SevillaRan2019 to 2021Enrolled291ConditionsAppendicitis Acute, AppendectomyArmsOutpatient (OA), Hospitalization appendectomy (HA)
NCT05511194 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Safety and Efficacy of Enhanced Recovery After Surgery Therapeutic Protocol for Complicated Appendicitis in Children

TypeinterventionalSponsorInstituto Mexicano del Seguro SocialRan2022 to 2023Enrolled40ConditionsEnhanced Recovery After Surgery, Appendicitis, Children, OnlyArmsEnhanced Recovery After Surgery therapeutic protocol, Conventional management
NCT06059365 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Randomized Clinical Trial to Test the Efficacy and Safety of Outpatient Clinical Management of Urgent Laparoscopic Appendectomy in Complicated Acute Appendicitis

TypeinterventionalSponsorHJ23Ran2023 to 2023Enrolled92ConditionsAcute Appendicitis, Appendicitis Perforated, Appendicitis SuppurativeArmsHospitalization, Outpatient
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Observational
  6. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mario Trejo-AvilaDepartment of General and Endoscopic Surgery, Hospital General Dr. Manuel Gea González, 4800 Calzada de Tlalpan, 14080, Mexico, Mexico. mario.trejo.avila@gmail.com.ORCID http://orcid.org/0000-0001-9249-3321
Eduardo Cárdenas-LailsonDepartment of General and Endoscopic Surgery, Hospital General Dr. Manuel Gea González, 4800 Calzada de Tlalpan, 14080, Mexico, Mexico.
Carlos Valenzuela-SalazarDepartment of General and Endoscopic Surgery, Hospital General Dr. Manuel Gea González, 4800 Calzada de Tlalpan, 14080, Mexico, Mexico.
Jose Herrera-EsquivelDepartment of General and Endoscopic Surgery, Hospital General Dr. Manuel Gea González, 4800 Calzada de Tlalpan, 14080, Mexico, Mexico.
Mucio Moreno-PortilloDepartment of General and Endoscopic Surgery, Hospital General Dr. Manuel Gea González, 4800 Calzada de Tlalpan, 14080, Mexico, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAmbulatory laparoscopic appendectomy has gained popularity due to the improved understanding of patient selection criteria, the application of enhanced recovery pathways, and the potential for improving healthcare resource utilization. The aim of the review was to compare the morbidity and readmission rates between ambulatory and conventional laparoscopic appendectomy (LA).

methodsA systematic search was undertaken using PubMed, Embase, Cochrane, and Web of Science. Studies from 2014 to 2018, on adult patients undergoing ambulatory LA, were considered. Meta-analyses were conducted to pool the total number of complications and readmission events in the ambulatory and conventional groups.

resultsA total of 5 studies met our inclusion criteria accounting for 7079 total of patients with acute appendicitis treated by ambulatory LA and 6370 patients treated by conventional LA. We included four observational studies (two prospective and two retrospective) and one randomized controlled trial. Length of stay was significantly lower in the ambulatory group (mean difference = - 15.63 h, 95% CI = - 21.78 to - 9.49, P = < 0.00001). The relative risk (RR) of reoperation was 0.49 (95% CI = 0.12-1.95, P = 0.31). The results demonstrated a pooled RR of overall morbidity of 0.79 (95% CI = 0.65-0.97, P = 0.02) and a pooled RR of readmission of 0.72 (95% CI = 0.59-0.88, P = 0.002), both results favoring the ambulatory LA group.

conclusionThere is a lack of high-quality comparative studies making conclusive recommendations not possible at this time. Based on current data, ambulatory LA may be safe and feasible as compared with conventional LA.

Indexed as

Ambulatory CareAppendectomyLaparoscopyHumansMorbidityPublication BiasRiskTreatment OutcomeAcute appendicitisAmbulatory appendectomyERASLaparoscopic appendectomyOutpatient

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.