Evidence map›Paper›PMID 31273438›Full record

ArticleLung2019

I Say IOS You Say AOS: Comparative Bias in Respiratory Impedance Measurements.

Chris RuiWen Kuo, Sunny Jabbal, Brian Lipworth

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Lung, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Small airways dysfunction: associated factors, clinical aspects and new perspectives.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Respiratory oscillometry in monitoring lung transplant allograft function: a systematic scoping review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Clinical significance and applications of oscillometry.European respiratory review : an official journal of the European Respiratory Society · 2022
    Review
  17. Article
  18. Oscillometry of the respiratory system: a translational opportunity not to be missed.American journal of physiology. Lung cellular and molecular physiology · 2021
    Review
  19. Lung function monitoring in the era of respiratory pandemics.Clinical physiology and functional imaging · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chris RuiWen KuoScottish Centre for Respiratory Research, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, DD1 9SY, UK.
Sunny JabbalScottish Centre for Respiratory Research, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, DD1 9SY, UK.
Brian LipworthScottish Centre for Respiratory Research, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, DD1 9SY, UK. b.j.lipworth@dundee.ac.uk.ORCID 0000-0002-8140-2014
University of Dundee · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe forced oscillation technique (FOT) measures respiratory impedance during normal tidal breathing and requires minimal patient cooperation.

objectiveTo compare IOS and AOS devices in patients with asthma and COPD.

methodsWe compared two different FOT devices, namely impulse oscillometry using a loudspeaker (IOS: Jaeger Masterscreen) and airwave oscillometry using a vibrating mesh (AOS: Thorasys Tremoflo) for pre- and post-bronchodilator measurements in 84 patients with asthma and COPD.

resultsThe overall pattern of measurement bias was for higher resistance with IOS and higher reactance with AOS, this being the case in asthma and COPD separately. There were small but significantly higher values using IOS for resistance at 5 Hz (R5) and 20(19) Hz (R20(19)). In converse, values for reactance at 5 Hz (X5), reactance area (AX) and resonant frequency (Fres) were significantly higher using AOS but to a much larger extent. The difference in AX between devices was more pronounced in COPD than in asthma. Salbutamol reversibility as % change was greater in asthma than COPD patients with AX but not FEV1.

conclusionOur study showed evidence of better agreement for resistance than reactance when comparing IOS and AOS, perhaps inferring that AOS may be more sensitive at measuring reactance in patients with airflow obstruction.

Indexed as

Airway ResistanceAgedAlbuterolAsthmaBronchodilator AgentsEquipment DesignFemaleForced Expiratory VolumeHumansLungMaleMaximal Midexpiratory Flow RateMiddle AgedOscillometryPredictive Value of TestsPulmonary Disease, Chronic ObstructiveAlbuterolBronchodilator AgentsAirwave oscillometryAsthmaAsthma control questionnaireCOPDImpulse oscillometrySpirometry

Identifiers

PMID31273438
PMCPMC6647162
OpenAlexW2955069894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.