Trial reportIntensive care medicine2019
Continual hemodynamic monitoring with a single-use transesophageal echocardiography probe in critically ill patients with shock: a randomized controlled clinical trial.
Trial report in Intensive care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02048566 (ImaCor II Effects of Hemodynamic Monitoring Using the ImaCor Single Use Transesophageal Echocardiography Probe in Critically Ill Patients - a Randomized Controlled Trial), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ImaCor II Effects of Hemodynamic Monitoring Using the ImaCor Single Use Transesophageal Echocardiography Probe in Critically Ill Patients - a Randomized Controlled Trial
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- ESICM guidelines on circulatory shock and hemodynamic monitoring 2025.Intensive care medicine · 2025Guideline
- Sleep quality assessment in hospitalized postoperative surgical patients: a COSMIN-based systematic review.Frontiers in sleep · 2025Pooled it
- Estimated plasma volume for predicting sepsis-associated ARDS risk: a multicentre retrospective cohort study.BMJ open respiratory research · 2026Article
- Critical Care Ultrasonography for Cardiogenic Shock: A Scoping Review.Critical care explorations · 2026Article
- Point-of-Care Transesophageal Echocardiography in Emergency and Intensive Care: An Evolving Imaging Modality.Biomedicines · 2025Review
- Monitoring left ventricular function with MAPSE and critical care echocardiography.Intensive care medicine · 2025Article
- Continuous three-dimensional transesophageal echocardiography and deep learning for perioperative monitoring of left ventricular longitudinal function.European heart journal. Imaging methods and practice · 2025Article
- Continuous monitoring of left ventricular function in postoperative intensive care patients using artificial intelligence and transesophageal echocardiography.Intensive care medicine experimental · 2024Article
- Automatic assessment of left ventricular function for hemodynamic monitoring using artificial intelligence and transesophageal echocardiography.Journal of clinical monitoring and computing · 2024Article
- Feasibility of resuscitative transesophageal echocardiography at out-of-hospital emergency scenes of cardiac arrest.Scientific reports · 2023Article
- Fully automatic estimation of global left ventricular systolic function using deep learning in transoesophageal echocardiography.European heart journal. Imaging methods and practice · 2023Article
- Indications, Clinical Impact, and Complications of Critical Care Transesophageal Echocardiography: A Scoping Review.Journal of intensive care medicine · 2023Article
- Predictive factors for cerebrocardiac syndrome in patients with severe traumatic brain injury: a retrospective cohort study.Frontiers in neurology · 2023Article
- Machines that save lives in the intensive care unit: the ultrasonography machine.Intensive care medicine · 2022Review
- The use of critical care echocardiography in peri-arrest and cardiac arrest scenarios: Pros, cons and what the future holds.Journal of the Intensive Care Society · 2021Article
- Focus on ultrasound in intensive care.Intensive care medicine · 2020Article
- Hemodynamic monitoring using trans esophageal echocardiography in patients with shock.Annals of translational medicine · 2020Review
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMortality in circulatory shock is high. Enhanced resolution of shock may improve outcomes. We aim to determine whether adding hemodynamic monitoring with continual transesophageal echocardiography (hTEE) to usual care accelerates resolution of hemodynamic instability.
methods550 patients with circulatory shock were randomly assigned to four groups stratified using hTEE (hTEE vs usual care) and assessment frequency (minimum every 4 h vs 8 h). Primary outcome was time to resolution of hemodynamic instability, analyzed as intention-to-treat (ITT) analysis at day 6 and in a predefined secondary analysis at days 3 and 28.
resultsOf 550 randomized patients, 271 with hTEE and 274 patients with usual care were eligible and included in the ITT analysis. Time to resolution of hemodynamic instability did not differ within the first 6 days [hTEE vs usual care adjusted sub-hazard ratio (SHR) 1.20, 95% confidence interval (CI) 0.98-1.46, p = 0.067]. Time to resolution of hemodynamic instability during the 72 h of hTEE monitoring was shorter in patients with TEE (hTEE vs usual care SHR 1.26, 95% CI 1.02-1.55, p = 0.034). Assessment frequency had no influence. Time to resolution of clinical signs of hypoperfusion, duration of organ support, length of stay and mortality in the intensive care unit and hospital, and mortality at 28 days did not differ between groups.
conclusionsIn critically ill patients with shock, hTEE monitoring or hemodynamic assessment frequency did not influence resolution of hemodynamic instability or mortality within the first 6 days. TRIAL REGISTRATION AND STATISTICAL ANALYSIS PLAN: ClinicalTrials.gov Identifier: NCT02048566.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.