ArticleEye (London, England)2019
Prospective 2-year study of accelerated pulsed transepithelial corneal crosslinking outcomes for Keratoconus.
Article in Eye (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pulsed corneal crosslinking in the treatment of Keratoconus: a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Pooled it
- Pulsed light epithelium-off accelerated corneal collagen crosslinking with 30mW/cmInternational ophthalmology · 2025Article
- A Review of Keratoconus Cross-Linking Treatment Methods.Journal of clinical medicine · 2025Review
- Keratoconus.Nature reviews. Disease primers · 2024Article
- Transepithelial Accelerated Crosslinking for Progressive Keratoconus: A Critical Analysis of Medium-Term Treatment Outcomes.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Management of keratoconus: an updated review.Frontiers in medicine · 2023Review
- In Vivo Confocal Microscopy Evaluation in Patients with Keratoconus.Journal of clinical medicine · 2022Review
- Screening of Keratoconus Using Autokeratometer and Keratometer Keratoconus Index.Diagnostics (Basel, Switzerland) · 2021Article
- The impact of hybrid contact lenses on keratoconus progression after accelerated transepithelial corneal cross-linking.International ophthalmology · 2021Article
- Article
- Repeatability of corneal and epithelial thickness measurements with anterior segment optical coherence tomography in keratoconus.PloS one · 2021Article
- Corneal Biomechanical Properties in Varying Severities of Myopia.Frontiers in bioengineering and biotechnology · 2020Article
- Peripheral Cornea Crosslinking Before Deep Anterior Lamellar Keratoplasty.Medical hypothesis, discovery & innovation ophthalmology journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo report 2-year outcomes of transepithelial, accelerated, pulsed, corneal crosslinking (t-ACXL) for patients with progressive keratoconus.
methodsProspective, interventional case series at a university hospital tertiary referral centre. Forty eyes with progressive keratoconus undergoing t-ACXL were included. Treatment was performed with pulsed illumination (1 s on/1 s off) using 45 mW/cm
resultsThe mean patient age was 23.32 ± 5.18 years (SD) (range 14-42 years). The mean CDVA significantly improved from 0.38 ± 0.32 logMAR at baseline to 0.30 ± 0.21 logMAR at 24 months (P < 0.01). There was no significant difference in UDVA, MRSE, asymmetry indices, tomographic parameters and endothelial density. The improvement in visual acuity was inversely correlated with preoperative CDVA and preoperative K
conclusionsIn this prospective study, t-ACXL appeared safe and effective in halting progression of keratoconus within a follow-up period of 24 months.
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