ArticleScientific reports2019
Visceral adiposity index (VAI), lipid accumulation product (LAP), and product of triglycerides and glucose (TyG) to discriminate prediabetes and diabetes.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 1 of them a synthesis that pooled it.
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Who cites it
136 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association Between Visceral Obesity Index and Diabetes: A Systematic Review and Meta-analysis.The Journal of clinical endocrinology and metabolism · 2024Pooled it
- Exercise-induced effects on asprosin and indices of atherogenicity and insulin resistance in males with metabolic syndrome: a randomized controlled trial.Scientific reports · 2024Trial
- Pentraxin 3 and the TyG Index as Two Novel Markers to Diagnose NAFLD in Children.Disease markers · 2021Trial
- Article
- Association between the cumulative average triglyceride-glucose-waist circumference index and new-onset hypertension among Chinese middle-aged and older adults-a national prospective study.Cardiovascular diabetology. Endocrinology reports · 2026Article
- Article
- Metabolic dysfunction and insulin resistance across major dementias: A comprehensive narrative review of the TyG index as a predictive marker.Metabolism open · 2026Review
- Association Between Low Chinese Visceral Adiposity Index Values and Chronic Lung Disease in Older Adults: Cohort Study.JMIR public health and surveillance · 2026Article
- Associations between lipid accumulation indices and gallstone prevalence in Chinese elderly: a community-based study in Fuzhou.BMC gastroenterology · 2026Article
- A Cross-sectional Data Analysis between Serum Total Bilirubin and Potential Obesity Indices in US Adults.Current molecular medicine · 2026Article
- Association of obesity and lipid indexes with rapid kidney function decline and the progression to chronic kidney disease: a study from a large longitudinal cohort among middle-aged and older adults in China.Frontiers in medicine · 2026Article
- Association between novel obesity- and lipid-related indices and diabetes across different FBG among elderly: a prospective cohort study.Frontiers in endocrinology · 2026Article
- A comparative analysis of anthropometric indices for identifying prediabetes in US adults: results from NHANES 2021-2023.Preventive medicine reports · 2026Article
- Assessing the Discriminative Power of Metabolic Indices for PMOS Detection in Normal-Weight Women.International journal of women's health · 2026Article
- Joint association of triglyceride-glucose index and Chinese visceral adiposity index with prevalent diabetes: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Anthropometric and lipid indices in relation to prediabetes and diabetes: A cross-sectional study in resource-limited areas of northwestern China.Journal of diabetes investigation · 2025Article
- Chinese visceral adiposity index outperforms other obesity indexes in association with increased overall cancer incidence: findings from prospective MJ cohort study.British journal of cancer · 2025Article
- Triglyceride-glucose index: a novel assessment tool for all-cause mortality in critical stroke patients-a retrospective analysis of the eICU-CRD database.Cardiovascular diabetology · 2025Observational
- The role of Triglyceride-Glucose index in predicting pre-DM risk among Chinese adults.Scientific reports · 2025Article
- Associations of water intake and Intra-Meal fluid consumption with obesity, insulin resistance, and predictors of cardiovascular diseases among Iranian women.Scientific reports · 2025Article
76 more citing papers are in PubMed but not listed here.
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Abstract
The present study evaluated the ability of the visceral adiposity index (VAI), the lipid accumulation product (LAP), and product of triglycerides and glucose (TyG), three novel, insulin resistance-related markers, to discriminate prediabetes/diabetes in the general German population. Altogether 2,045 Germans (31-72 years, 53.3% women) without known diabetes and a history of Myocardial Infarction (MI)/stroke from the Cooperative Health Research in the Region of Augsburg (KORA) F4 Study were eligible. The discriminatory accuracy of the markers for oral glucose tolerance test (OGTT)-defined prediabetes/diabetes according to the American Diabetes Association (ADA) criteria was assessed by the area under the receiver operating characteristic (ROC) curve (AUC). The Youden Index (YI) was used to determine optimal cut-off values, and a non-parametric ROC regression was used to examine whether the discriminatory accuracy varied by sex and age. 365 men (38.2%) and 257 women (23.6%) were newly diagnosed with prediabetes/diabetes. AUCs for TyG, LAP and VAI were 0.762 (95% CI 0.740-0.784), 0.743 (95% CI 0.720-0.765), and 0.687 (95% CI 0.662-0.712), respectively. The optimal cut-off values for the LAP and TyG were 56.70 and 8.75 in men, and 30.40 and 8.53 in women. In conclusion, TyG and LAP provide good discrimination of persons with prediabetes/diabetes.
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