ArticleScientific reports2019
A Characterization of the DNA Data Storage Channel.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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Who cites it
60 citing papers in PubMed.
- Engineered eMutS based magnetic separation system for high-fidelity DNA synthesis.Synthetic and systems biotechnology · 2026Article
- Highly biased DNA sequence reconstruction in DNA storage with multi-scale attention mechanism and contrast learning.Synthetic and systems biotechnology · 2026Article
- Modeling DNA storage retrieval reliability via sequencing coverage depth.Briefings in bioinformatics · 2026Article
- Large-Scale Distribution of Physical Data Using DNA-of-Things Technology in Newspaper Printing.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- From spacecraft ranging to massive DNA data storage: Composite ranging codes as indices and error correction references.Science advances · 2026Article
- Comparison of state-of-the-art error-correction coding for sequence-based DNA data storage.Nature communications · 2026Article
- Advances and challenges in non-canonical nucleic acids data storage.Nature communications · 2026Review
- DPCM-DP-EN: a lossless dynamic compress and encrypted encode method for DNA storage of medical images with high storage density.Medical & biological engineering & computing · 2026Article
- Article
- Trade-offs in model compression for sequencing data-carrying DNA.Scientific reports · 2025Article
- Evaluation of multiplexed liquid glycan Array (LiGA) for serological detection of glycan-binding antibodies.Glycobiology · 2025Article
- Achieving handle-level random access in an encrypted DNA archival storage system via frequency dictionary mapping coding.Patterns (New York, N.Y.) · 2025Article
- Dna-storalator: a computational simulator for DNA data storage.BMC bioinformatics · 2025Article
- Predict the degree of secondary structures of the encoding sequences in DNA storage by deep learning model.Scientific reports · 2025Article
- Sequence analysis and decoding with extra low-quality reads for DNA data storage.Bioinformatics (Oxford, England) · 2025Article
- DNA storage: The future direction for medical cold data storage.Synthetic and systems biotechnology · 2025Review
- Pragmatic soft-decision data readout of encoded large DNA.Briefings in bioinformatics · 2025Article
- Massively parallel homogeneous amplification of chip-scale DNA for DNA information storage (MPHAC-DIS).Nature communications · 2025Article
- Biotechnological tools boost the functional diversity of DNA-based data storage systems.Computational and structural biotechnology journal · 2025Review
- DNA palette code for time-series archival data storage.National science review · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Owing to its longevity and enormous information density, DNA, the molecule encoding biological information, has emerged as a promising archival storage medium. However, due to technological constraints, data can only be written onto many short DNA molecules that are stored in an unordered way, and can only be read by sampling from this DNA pool. Moreover, imperfections in writing (synthesis), reading (sequencing), storage, and handling of the DNA, in particular amplification via PCR, lead to a loss of DNA molecules and induce errors within the molecules. In order to design DNA storage systems, a qualitative and quantitative understanding of the errors and the loss of molecules is crucial. In this paper, we characterize those error probabilities by analyzing data from our own experiments as well as from experiments of two different groups. We find that errors within molecules are mainly due to synthesis and sequencing, while imperfections in handling and storage lead to a significant loss of sequences. The aim of our study is to help guide the design of future DNA data storage systems by providing a quantitative and qualitative understanding of the DNA data storage channel.
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