Evidence map›Paper›PMID 31273223›Full record

ArticleScientific reports2019

Crystal Protein of a Novel Bacillus thuringiensis Strain Inducing Cell Cycle Arrest and Apoptotic Cell Death in Human Leukemic Cells.

V Beena, V Ramnath, K P Sreekumar, K Karthiayini, P T Philomina, D Girija

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. AX-2: A Promising Non-Hemolytic Protein ofMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

V BeenaDepartment of Veterinary Physiology, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, Thrissur, Kerala, India. beena100030@rediffmail.com.
V RamnathDepartment of Veterinary Physiology, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, Thrissur, Kerala, India.
K P SreekumarDepartment of Veterinary Physiology, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, Thrissur, Kerala, India.
K KarthiayiniDepartment of Veterinary Physiology, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, Thrissur, Kerala, India.
P T PhilominaDepartment of Veterinary Physiology, College of Veterinary and Animal Sciences, Mannuthy, Kerala Veterinary and Animal Sciences University, Thrissur, Kerala, India.
D GirijaDepartment of Agricultural Microbiology, College of Horticulture, Kerala Agricultural University, Vellanikkara, Thrissur, Kerala, India.
Kerala Veterinary and Animal Sciences University · INKerala Agricultural University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parasporal inclusions of a native non haemolytic Bacillus thuringiensis strain KAU 59 was screened for its cytotoxicity against human lymphocytic leukemic cell line jurkat and normal human lymphocytes. The cytotoxicity of proteinase activated and non activated solubilised parasporal inclusions against both cell lines was assessed by Cell Titer 96 Aqueous Non Radioactive Cell Proliferation Assay Kit using MTS. The 50 per cent effective concentration (EC

Indexed as

ApoptosisCell Cycle CheckpointsAntineoplastic AgentsBacillus thuringiensis ToxinsBacterial ProteinsEndotoxinsHemolysin ProteinsHemolysisHumansLeukemiaTumor Cells, CulturedAntineoplastic AgentsBacillus thuringiensis ToxinsBacterial ProteinsEndotoxinsHemolysin Proteinsinsecticidal crystal protein, Bacillus Thuringiensis

Identifiers

PMID31273223
PMCPMC6609778
OpenAlexW2954597326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.