Evidence map›Paper›PMID 31273056›Full record

ArticleBioscience reports2019

MicroRNA-222 promotes drug resistance to doxorubicin in breast cancer via regulation of miR-222/bim pathway.

Hong Dai, Ling-Yun Xu, Qi Qian, Qiu-Wei Zhu, Wei-Xian Chen

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. miRNAs as short non-coding RNAs in regulating doxorubicin resistance.Journal of cell communication and signaling · 2023
    Review
  8. Review
  9. Review
  10. Article
  11. Breast Cancer Response to Therapy: Can microRNAs Lead the Way?Journal of mammary gland biology and neoplasia · 2021
    Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hong DaiDepartment of Breast Surgery, the Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213000, China.
Ling-Yun XuDepartment of Breast Surgery, the Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213000, China.
Qi QianDepartment of Breast Surgery, the Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213000, China.
Qiu-Wei ZhuDepartment of Breast Surgery, the Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213000, China chenweixian@njmu.edu.cn zhuqiuweidoc@outlook.com.
Wei-Xian ChenDepartment of Breast Surgery, the Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou 213000, China chenweixian@njmu.edu.cn zhuqiuweidoc@outlook.com.ORCID 0000-0003-0025-4476
Changzhou No.2 People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance to doxorubicin (DOX) is the most common clinical problem in breast cancer therapy, and the underlying molecular mechanism remains to be investigated. MicroRNAs (miRNAs) exhibit important regulatory functions in various malignant tumors including breast cancer. The aim of the present study was to find the relationship between

Indexed as

Drug Resistance, NeoplasmSignal TransductionBreast NeoplasmsDoxorubicinFemaleHumansMCF-7 CellsMicroRNAsRNA, NeoplasmDoxorubicinMicroRNAsMIR222, humanRNA, NeoplasmBreast cancerChemoresistanceDoxorubicinmiR-222

Identifiers

PMID31273056
PMCPMC6629945
OpenAlexW2955918525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.