ArticleAlzheimer's research & therapy2019
Associations between quantitative [
Article in Alzheimer's research & therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 51 citations in OpenAlex.
- Classification of tau status with machine learning models in amyloid-positive cohorts.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Multimodal neuroimaging approach for cognitive impairment in Alzheimer's disease.medRxiv : the preprint server for health sciences · 2026Article
- Bayesian modelling demonstrates clinically relevant heterogeneity in Tau PET patterns in Alzheimer's disease.European journal of nuclear medicine and molecular imaging · 2026Article
- Spatial patterns of tau accumulation across the Alzheimer's disease spectrum.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- The Role of Tau in Neuronal Function and Neurodegeneration.Neurology international · 2025Review
- High-molecular-weight oligomer tau (HMWoTau) species are dramatically increased in Braak-stage dependent manner in the frontal lobe of human brains, demonstrated by a novel oligomer Tau ELISA with a mouse monoclonal antibody (APNmAb005).FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- The spatial distribution of coupling between tau and neurodegeneration in amyloid-β positive mild cognitive impairment.Neurobiology of aging · 2024Article
- Regional Tau Deposition Reflects Different Pathways of Subsequent Neurodegeneration and Memory Decline in Cognitively Normal Older Adults.Annals of neurology · 2024Article
- The characteristics of brain atrophy prior to the onset of Alzheimer's disease: a longitudinal study.Frontiers in aging neuroscience · 2024Article
- A review of the flortaucipir literature for positron emission tomography imaging of tau neurofibrillary tangles.Brain communications · 2024Review
- Association of Pathologic and Volumetric Biomarker Changes With Cognitive Decline in Clinically Normal Adults.Neurology · 2023Article
- Tau: a biomarker of Huntington's disease.Molecular psychiatry · 2023Review
- The Use of Tau PET to Stage Alzheimer Disease According to the Braak Staging Framework.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023Review
- An Imbalance in the Pro/mature BDNF Ratio Occurs in Multiple Brain Regions During Normal Ageing in Wild-Type Mice.Journal of molecular neuroscience : MN · 2023Article
- Longitudinal Tau PET UsingJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023Article
- Identification of multimodal brain imaging association via a parameter decomposition based sparse multi-view canonical correlation analysis method.BMC bioinformatics · 2022Article
- The Evolution of Diagnostic Boundaries of Alzheimer's Disease and Novel Therapeutic Options: Эволюция диагностических границ болезни Альцгеймера и новые терапевтические возможности.Consortium psychiatricum · 2022Article
- SPARE-Tau: A flortaucipir machine-learning derived early predictor of cognitive decline.PloS one · 2022Article
- The Legacy of the TTASAAN Report - Premature Conclusions and Forgotten Promises About SPECT Neuroimaging: A Review of Policy and Practice Part II.Frontiers in neurology · 2022Article
- Tau Biomarkers in Dementia: Positron Emission Tomography Radiopharmaceuticals in Tauopathy Assessment and Future Perspective.International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundNeuropathological studies have linked tau aggregates to neuronal loss. To describe the spatial distribution of neurofibrillary tangle pathology in post-mortem tissue, Braak staging has been used. The aim of this study was to examine in vivo associations between tau pathology, quantified with [
methodsWe included 100 subjects, including 58 amyloid-β positive patients with mild cognitive impairment (MCI, n = 6) or AD dementia (n = 52) and 42 controls with subjective cognitive decline (36% amyloid-β positive). All subjects underwent a dynamic [
resultsIn MCI/AD subjects (age [mean ± SD] 65 ± 8 years, MMSE 23 ± 4), [
conclusionsIn MCI/AD patients, [
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.