Evidence map›Paper›PMID 31272481›Full record

ArticleLipids in health and disease2019

Age-related and gender-stratified differences in the association between high triglyceride and risk of hyperuricemia.

Lei Zhang, Qilin Wan, Yuemin Zhou, Jing Xu, Chengyun Yan, Yuanyuan Ma, Minglong Xu, Ruili He, Yanming Li, Xiaoming Zhong and 2 more

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Associations between multiple essential trace metal concentrations and risk of hyperuricemia: insights from a central Chinese population.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Lei ZhangDepartment of Cardiology, Huaihe Hospital of Henan University, No. 8 Baobei Road, Kaifeng, 475000, China.
Qilin WanDepartment of Cardiology, Huaihe Hospital of Henan University, No. 8 Baobei Road, Kaifeng, 475000, China.
Yuemin ZhouInternational Joint Research Laboratory for Cell Medical Engineering of Henan, Huaihe Hospital of Henan University, No. 115 Ximen Street, Kaifeng, 475000, China.
Jing XuDepartment of Cardiology, Huaihe Hospital of Henan University, No. 8 Baobei Road, Kaifeng, 475000, China.
Chengyun YanDepartment of Cardiology, Huaihe Hospital of Henan University, No. 8 Baobei Road, Kaifeng, 475000, China.
Yuanyuan MaInternational Joint Research Laboratory for Cell Medical Engineering of Henan, Huaihe Hospital of Henan University, No. 115 Ximen Street, Kaifeng, 475000, China.
Minglong XuDepartment of Physical Examination Center, Huaihe Hospital of Henan University, No. 8 Baobei Road, Kaifeng, 475000, China.
Ruili HeDepartment of Cardiology, Huaihe Hospital of Henan University, No. 8 Baobei Road, Kaifeng, 475000, China.
Yanming LiDepartment of Cardiology, Huaihe Hospital of Henan University, No. 8 Baobei Road, Kaifeng, 475000, China.
Xiaoming ZhongDepartment of Cardiology, Huaihe Hospital of Henan University, No. 8 Baobei Road, Kaifeng, 475000, China.
Guanchang ChengDepartment of Cardiology, Huaihe Hospital of Henan University, No. 8 Baobei Road, Kaifeng, 475000, China. Mike0092@126.com.
Yuquan LuInternational Joint Research Laboratory for Cell Medical Engineering of Henan, Huaihe Hospital of Henan University, No. 115 Ximen Street, Kaifeng, 475000, China. lll3923@gmail.com.
Henan University Huaihe Hospital and Huaihe Clinical Institute · CN

Funding

Scientific and Technological Project of Henan Province 201502017
6 · The paper itself

Abstract

backgroundElevated serum uric acid is commonly associated with high triglyceride. However, the relation of triglyceride and hyperuricemia in different gender and age groups is currently not well understood. This study aimed to evaluate age- and gender-related association of high triglyceride with hyperuricemia in a subgroup of Chinese population.

methodsWe retrospectively analyzed physical examination data of 24,438 subjects (12,557 men and 11,881 women) in Kaifeng, China. The alanine aminotransferase, γ-glutamyl transpeptidase, serum creatinine, blood urea nitrogen, total cholesterol, high-density lipoprotein cholesterol, triglyceride and serum uric acid were measured in all subjects. The triglyceride was categorized into < 1.21, 1.21 ~, 1.7 ~, 2.83 ~ and >  5.6 mmol/L subgroups, and odds ratio (OR) and 95% confidence interval (CI) of hyperuricemia were calculated by logistic regression analysis.

resultsUnivariate and age-adjusted analyses showed that high triglyceride was positively associated with hyperuricemia (p <  0.01). Further age-stratified analysis showed that the positive association was significant in the 20 ~, 30 ~, 40 ~, 50 ~, 60 ~ and 80 ~ age groups in men. In women, no statistically significant was found in 60 ~ and 70 ~ age groups.

conclusionHigh triglyceride is positively associated with hyperuricemia in both men and women, and this association is age-related, especially in women.

Indexed as

AdultAgedAged, 80 and overAge FactorsFemaleHumansHyperuricemiaLogistic ModelsMaleMiddle AgedOdds RatioRetrospective StudiesRisk FactorsSex FactorsTriglyceridesUric AcidTriglyceridesUric AcidAge-relatedHyperuricemiaRiskTriglyceride

Identifiers

PMID31272481
PMCPMC6611049
OpenAlexW2954895999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.