Evidence map›Paper›PMID 31272473›Full record

Trial reportRadiation oncology (London, England)2019

Primary adenoid cystic carcinoma of the trachea: clinical outcome of 38 patients after interdisciplinary treatment in a single institution.

Benjamin A Högerle, Felix Lasitschka, Thomas Muley, Nina Bougatf, Klaus Herfarth, Sebastian Adeberg, Martin Eichhorn, Jürgen Debus, Hauke Winter, Stefan Rieken and 1 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Radiation oncology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Treatment and outcomes of minor salivary gland cancers of the larynx and trachea: a systematic review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2023
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Benjamin A HögerleDepartment of Thoracic Surgery, Thoraxklinik, Heidelberg University Hospital, Röntgenstraße 1, 69126, Heidelberg, Germany.
Felix LasitschkaInstitute of Pathology, Heidelberg University Hospital, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.
Thomas MuleyTranslational Research Unit, Thoraxklinik, Heidelberg University Hospital, Member of the German Center for Lung Research, Röntgenstraße 1, 69126, Heidelberg, Germany.
Nina BougatfDepartment of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Klaus HerfarthDepartment of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Sebastian AdebergDepartment of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Martin EichhornDepartment of Thoracic Surgery, Thoraxklinik, Heidelberg University Hospital, Röntgenstraße 1, 69126, Heidelberg, Germany.
Jürgen DebusDepartment of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Hauke WinterDepartment of Thoracic Surgery, Thoraxklinik, Heidelberg University Hospital, Röntgenstraße 1, 69126, Heidelberg, Germany.
Stefan RiekenDepartment of Radiation Oncology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Matthias UhlNational Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), 69120, Heidelberg, Germany. matthias.uhl@med.uni-heidelberg.de.
Heidelberg University · DEUniversity Hospital Heidelberg · DENational Center for Tumor Diseases · DEGerman Center for Lung Research · DEHeidelberger Institut für Radioonkologie · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary adenoid cystic carcinomas (ACCs) of the trachea are rare tumors of the central bronchial system. In patients presenting with unresectable tumors, severe comorbidities, or incomplete surgical resection, definitive radiotherapy is currently the recommended treatment. Irradiation with carbon ions (C

methodsAll patients with histologically confirmed ACC of the trachea treated with surgery and/or radiation treatment at Heidelberg University Hospital between 1991 and 2017 were included in this analysis. Patient and treatment characteristics, short- and long-term toxicity after radiotherapy, overall survival (OS), freedom from local progression (FFLP), and freedom from distant progression (FFDP) were prospectively acquired and retrospectively analyzed.

resultsThirty-eight patients (23 women and 15 men) with a median age of 51 were treated by surgery (n = 20) and/or radiotherapy with either C

conclusionsThe long-term prognosis is favorable if surgery is performed. In cases of an incomplete resection, good OS can still be achieved following adjuvant radiotherapy. For radiotherapy, irradiation with C

trial registrationThe ethics committee of the Heidelberg University Hospital approved the retrospective data analysis (S-174/2019).

Indexed as

Patient Care TeamAdultAgedAged, 80 and overCarcinoma, Adenoid CysticCombined Modality TherapyFemaleHumansMaleMiddle AgedPrognosisProspective StudiesRetrospective StudiesSurvival RateTracheal NeoplasmsYoung AdultAdenoid cystic carcinomaCarbon ionCarcinoma of the tracheaMulti-modal treatmentRadiation therapyTracheal tumor surgery

Identifiers

PMID31272473
PMCPMC6610895
OpenAlexW2953981192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.