Observational studyJournal of orthopaedic surgery and research2019
Mortality after osteoporotic hip fracture: incidence, trends, and associated factors.
Observational study in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05025228 (Analgesic Effect of Paracetamol in Patients With Femur Fracture), which is not on this map. Cited by 288 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Analgesic Effect of Paracetamol in Patients With Femur Fracture: is Intravenous Better Than Oral?
Who cites it
288 citing papers in PubMed, 8 syntheses or guidelines pooled it, 465 citations in OpenAlex.
- Effects of Potassium Citrate Supplementation on Bone Turnover Markers in Postmenopausal Women: A GRADE-Assessed Systematic Review, Meta-analysis and Trial Sequential Analysis.Calcified tissue international · 2026Pooled it
- Health and adverse events associated with extended oral bisphosphonates among postmenopausal women: a systematic review.The Journal of clinical endocrinology and metabolism · 2026Pooled it
- Global, Regional and National Estimates of Hip Fracture Burden Associated with Type 2 Diabetes in Adults Aged Over 40 from 1990 to 2021 and Projections to 2046.Calcified tissue international · 2025Pooled it
- Surgical approaches for inserting hemiarthroplasty of the hip in people with hip fractures.The Cochrane database of systematic reviews · 2025Pooled it
- Malnutrition-Related Health Outcomes in Older Adults with Hip Fractures: A Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- The Association between Red Blood Cell Distribution Width and Mortality Risk after Hip Fracture: A Meta-Analysis.Medicina (Kaunas, Lithuania) · 2024Pooled it
- O-POSSUM and P-POSSUM as predictors of morbidity and mortality in older patients after hip fracture surgery: a meta-analysis.Archives of orthopaedic and trauma surgery · 2023Pooled it
- The prevalence of osteoporotic fractures in the elderly in China: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Trial
- Concurrent effects of high-intensity interval training and vitamin D supplementation on bone metabolism among women diagnosed with osteoporosis: a randomized controlled trial.BMC musculoskeletal disorders · 2025Trial
- Twelve-month resistance and impact exercise program or risedronate provides a relative benefit to hip bone structure in postmenopausal women: results from a randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Trial
- Osteoporosis medication initiation after proximal humerus fractures is low, but associated with decreased secondary fragility fracture risk.OTA international : the open access journal of orthopaedic trauma · 2026Article
- Fecal and urinary incontinence in older men with hip fracture: a geriatric syndrome with prognostic significance.European geriatric medicine · 2026Article
- Article
- Mortality and Risk Factors After Hip Fracture in Patients Aged 50 Years and Older: A Minimum 10-Year Follow-up Using Jeju Island Cohort Study.Journal of Korean medical science · 2026Article
- Development of a Multimodal Machine Learning Model for Predicting Second Osteoporotic Vertebral Compression Fractures.Yonsei medical journal · 2026Article
- Effectiveness and safety of denosumab on osteoporosis treatment in kidney transplant recipients.Kidney research and clinical practice · 2026Article
- Assessing Impact of Orthopedic Subspecialty Training on Outcomes of Non-Arthroplasty Fixation of Geriatric Hip Fractures.Hip & pelvis · 2026Article
- Long-Term Trends of Distal Radius Fractures in Adults Aged ≥ 50 Years in Korea Using Nationwide Claims Database (2006-2022).Journal of Korean medical science · 2026Article
- Overall and Relative Survival After a Second Contralateral Hip Fracture in Adults over 65 Years: A Retrospective Cohort Study.Geriatrics (Basel, Switzerland) · 2026Article
228 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is known that mortality after hip fracture increases compared to the general population; the trend in mortality is a controversial issue. The objective of this study is to examine incidence, trends, and factors associated with mortality in patients with osteoporotic hip fractures.
methodsThis is a retrospective cohort study that uses the Registry for Hospital Discharges of the National Health System of our hospital. Patients older than 45 having an osteoporotic hip fracture between 1999 and 2015 were identified. Demographic data and comorbidities were obtained. A survival analysis was performed (Cox regression and Kaplan-Meier). Incidence rate, standardized death rate (SDR), trend (Poisson regression), and risk (hazard ratio) were calculated.
resultsDuring 1999-2015, in our hospital, there were a total of 3992 patients admitted due to osteoporotic hip fracture. Out of these 3992 patients, 3109 patients (77.9%) were women with an average age of 84.47 years (SD 8.45) and 803 (22.1%) were men with an average age of 81.64 years (SD 10.08). The cumulative incidence of mortality was 69.38%. The cumulative mortality rate for 12 months was 33%. The annual mortality was 144.9/1000 patients/year. The 1-year mortality rate increased significantly by 2% per year (IRR 1.020, CI95% 1.008-1.033). The median overall survival was 886 days (CI95% 836-951). The probability of mortality density for a period of 10 years following a hip fracture was 16% for women and 25% for men (first 90 days). The SDR was 8.3 (CI95% 7.98-8.59). Variables that showed statistically significant association with mortality were aged over 75, masculine, institutionalization, mild to severe liver disease, chronic kidney disease, COPD, dementia, heart failure, diabetes, the Charlson Index > 2 , presence of vision disorders and hearing impairment, incontinence, and Downton scale.
conclusionsFor the last 17 years, an increase of mortality for patients with hip fracture and a higher mortality rate in men than in women were observed. Institutionalization combined with comorbidities is associated with a higher mortality.
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