Evidence map›Paper›PMID 31272450›Full record

ArticleLipids in health and disease2019

Bio-evaluation of functional date bars using rats as model organism against hypercholesterolemia.

Muhammad Sajid Arshad, Syeda Mamoona Batool, Muhammad Kamran Khan, Muhammad Imran, Muhammad Haseeb Ahmad, Faqir Muhammad Anjum, Shahzad Hussain

Abstract read
In one paragraph

Article in Lipids in health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Nutraceuticals ofDrug design, development and therapy · 2026
    Review
  5. Article
  6. Date Palm Fruit (Nutrients · 2023
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muhammad Sajid ArshadInstitute of Home and Food Sciences, Government College University, Faisalabad, Pakistan. sajid_ft@yahoo.com.ORCID http://orcid.org/0000-0001-9564-886X
Syeda Mamoona BatoolInstitute of Home and Food Sciences, Government College University, Faisalabad, Pakistan.
Muhammad Kamran KhanInstitute of Home and Food Sciences, Government College University, Faisalabad, Pakistan.
Muhammad ImranInstitute of Home and Food Sciences, Government College University, Faisalabad, Pakistan.
Muhammad Haseeb AhmadInstitute of Home and Food Sciences, Government College University, Faisalabad, Pakistan.
Faqir Muhammad AnjumVice Chancellor Secretariat, University of the Gambia, Banjul, The Gambia.
Shahzad HussainCollege of Food and Agricultural Sciences, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present research project was designed to evaluate the cholesterol lowering potential of different date varieties including one exotic (Ajwa) and three Pakistani varieties (Aseel, Khudravi, Hallawi).

methodsThe albino rats were divided into six groups on the basis of different diets which includes, control having basal diet, high cholesterol high sucrose diet, high cholesterol high sucrose diet plus Khudravi dates, high cholesterol high sucrose diet plus Hallawi dates, high cholesterol high sucrose diet plus Aseel dates, high cholesterol high sucrose diet plus Ajwa dates to evaluate maximum cholesterol lowering potential of each date variety.

resultsThe results showed that Hallawi and Ajwa have lower crude fiber content as 2.02 ± 0.03% and 2.43 ± 0.04% however, lowest crude fat content (0.26 ± 0.01%) was also observed in ajwa. Mineral profile depicted that sodium (9.50-18.00 mg/100 g) was found to be in lesser amount among all varieties whereas, higher amount of potassium (465.00 to 887.20 mg/100 g) depicted that it is suitable for people having hypertension. Higher amount of reducing sugar was also observed in ajwa (79.45 ± 1.22%) followed by Hallawi (77.68 ± 1.42%). Total phenolic contents were found higher in Aseel (291.36 mg/100 g) whereas, minimum was observed in Khudravi (232.64 mg/100 g). Furthermore, date varieties were also examined rat modeling to evaluate their maximum cholesterol lowering efficiency. Ajwa and Hallawi were observed to suppress the cholesterol efficiently as 110 mg/dL and 103 mg/dL respectively. On the basis of chemical profiling and other parameters, two date varieties Ajwa and Hallawi showed almost similar results and found to have maximum serum cholesterol, LDL and triglyceride reduction potential with good kidney and liver functions. Functional date bar was also developed by using Hallawi variety andsubjected to sensory evaluation.

conclusionIn nutshell, Hallawi date variety was considered as better cholesterol lowering potential among other indigenous varieties and very close to Ajwa variety. So that Hallawi can be used to suppress the deadly effects of obesity and allied discrepancies particularly hypercholesterolemia.

Indexed as

Functional FoodAnimalsAntioxidantsCholesterolDisease Models, AnimalHumansHypercholesterolemiaLipoproteins, HDLLipoproteins, LDLMaleMineralsNutritive ValuePakistanPhenolsPhoeniceaeRats, Sprague-DawleyAntioxidantsCholesterolLipoproteins, HDLLipoproteins, LDLMineralsPhenolsTriglyceridesAntioxidant profileDate varietiesHypercholesterolemiaRats modelling

Identifiers

PMID31272450
PMCPMC6610949

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.