Evidence map›Paper›PMID 31272204›Full record

ArticleJournal of diabetes science and technology2021

Improved Real-World Glycemic Control With Continuous Glucose Monitoring System Predictive Alerts.

Sinu Bessy Abraham, Siddharth Arunachalam, Alex Zhong, Pratik Agrawal, Ohad Cohen, Chantal M McMahon

Abstract read
In one paragraph

Article in Journal of diabetes science and technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Insights into the effective use of the Smart MDI system: Data from the first 1852 type 1 diabetes users.Diabetic medicine : a journal of the British Diabetic Association · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Criteria for Personalised Choice of a Continuous Glucose Monitoring System: An Expert Opinion.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Article
  11. Article
  12. Diabetes management in the era of artificial intelligence.Archives of medical sciences. Atherosclerotic diseases · 2024
    Article
  13. Article
  14. Observational
  15. Article
  16. Review
  17. Article
  18. Artificial intelligence perspective in the future of endocrine diseases.Journal of diabetes and metabolic disorders · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sinu Bessy AbrahamMedtronic, Northridge, CA, USA.
Siddharth ArunachalamMedtronic, Northridge, CA, USA.
Alex ZhongMedtronic, Northridge, CA, USA.
Pratik AgrawalMedtronic, Northridge, CA, USA.
Ohad CohenMedtronic, Tolochenaz, Switzerland.
Chantal M McMahonMedtronic, Northridge, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost standalone real-time continuous glucose monitoring (RT-CGM) systems provide predictive low and high sensor glucose (SG) threshold alerts. The durations and risk of low and high SG excursions following Guardian™ Connect CGM system predictive threshold alerts were evaluated.

methodsContinuous glucose monitoring system data uploaded between January 2, 2017 and May 22, 2018 by 3133 individuals using multiple daily injections (MDIs) or continuous subcutaneous insulin infusion (CSII) therapy were deidentified and retrospectively analyzed. Glucose excursions were defined as SG values that went beyond a preset low or high SG threshold for ≥15 minutes. For a control group, thresholds were based on the median of the low SG threshold limit (70 mg/dL) and the high SG threshold limit (210 mg/dL) preset by all system users. During periods when alerts were not enabled, timestamps were identified when a predictive alert would have been triggered. The time before low horizon was 17.5 minutes and the time before high horizon was 15 minutes, of all users who enabled alerts. Excursions occurring after a low SG or high SG predictive alert were segmented into prevented, ≤20, 20-60, and >60 minutes.

resultsExcursions were prevented after 59% and 39% of low and high SG predictive alerts, respectively. The risk of a low or high excursion occurring was 1.9 (

conclusionsThe predictive alerts of the RT-CGM system under study can help individuals living with diabetes prevent some real-world low and high SG excursions. This can be especially important for those unable to reach or maintain glycemic control with basic RT-CGM or CSII therapy.

Indexed as

Blood Glucose Self-MonitoringDiabetes Mellitus, Type 1Blood GlucoseGlucoseGlycemic ControlHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsRetrospective StudiesBlood GlucoseGlucoseHypoglycemic AgentsInsulincontinuous glucose monitoringhyperglycemiahypoglycemiapredictive threshold alertstype 1 diabetestype 2 diabetes

Identifiers

PMID31272204
PMCPMC7783013

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.