Evidence map›Paper›PMID 31271842›Full record

ArticleJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus2019

Feasibility of monitoring compliance with intermittent occlusion therapy glasses for amblyopia treatment.

Jingyun Wang, Jing Jin, Ayesha Malik, Ruth Shoge, Siva Meiyeppen, Yi Pang, Kelly Yin, Megan Allen, Brandy Scombordi, Ajay Soni and 2 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Current Management of Childhood Amblyopia.Korean journal of ophthalmology : KJO · 2019
    Review
  8. [Treatment monitoring and innovations in amblyopia treatment].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Jingyun WangSalus Univerisity, Elkins Park, Pennsylvania, United States. Electronic address: jwang@salus.edu.
Jing JinNemours/Alfred I. duPont Hospital for Children, Wilmington, Delaware, United States; Wills Eye Hospital, Philadelphia, Pennsylvania, United States.
Ayesha MalikChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States.
Ruth ShogeSalus Univerisity, Elkins Park, Pennsylvania, United States.
Siva MeiyeppenSalus Univerisity, Elkins Park, Pennsylvania, United States.
Yi PangIllinois College of Optometry, Chicago, Illinois, United States.
Kelly YinIllinois College of Optometry, Chicago, Illinois, United States.
Megan AllenIllinois College of Optometry, Chicago, Illinois, United States.
Brandy ScombordiSalus Univerisity, Elkins Park, Pennsylvania, United States.
Ajay SoniPenn State Eye Center, Hershey, Pennsylvania, United States.
Daniel E NeelyGlick Eye Institute, Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, United States.
Kai JanuschowskiEye Clinic Sulzbach, Sulzbach/Saar, Germany; Department for Ophthalmology, Eberhard Karls University Tuebingen, Germany.
Salus University · USIllinois College of Optometry · USChildren's Hospital of Philadelphia · USIndiana University – Purdue University Indianapolis · USKnappschaftsklinikum Saar · DEPenn State Milton S. Hershey Medical Center · USWills Eye Hospital · US

Funding

Efficacy of Intermittent Occlusion in Amblyopia TreatmentR21EY026664 · NEI · SALUS UNIVERSITY · PI NEELY, DANIEL, WANG, JINGYUN · 2016 to 2017
$394k
NEI NIH HHS R21 EY026664
6 · The paper itself

Abstract

backgroundLiquid crystal glasses use an intermittent occlusion technique and may improve compliance compared to adhesive patches. Previous studies support the effectiveness of intermittent occlusion therapy (IO therapy) glasses for amblyopia treatment. However, objective compliance for these glasses has not been measured. The purpose of this study was to investigate the feasibility of using a microsensor to monitor objective compliance with IO therapy glasses.

methodsChildren 3 to ≤8 years of age with unilateral amblyopia were enrolled. All subjects had optimal refractive correction (if needed) for at least 5 weeks without improvement. Subjects were prescribed IO therapy glasses, set at 30-second opaque/transparent intervals (ie, occluded 50% of wear time). Wear time was prescribed according to amblyopia severity. For each patient, objective compliance with the IO therapy glasses was monitored by means of a microsensor.

resultsA total of 13 subjects returned with microsensor data. Compliance varied among and within individuals. General compliance averaged 51.6% (range, 10%-97%). Mean daily compliance decreased slightly over time. On average, patients' visual acuity improved 0.14 ± 0.15 logMAR (range, -0.1 to 0.5 logMAR). No parents reported that their child had social concerns related to the attached microsensor.

conclusionsObjective compliance with IO therapy glasses can be monitored by a simple microsensor reliably. In our study cohort, objective compliance with IO therapy glasses varied among individuals, but on average it declined slightly over time.

Indexed as

EyeglassesPatient ComplianceAmblyopiaChildChild, PreschoolEquipment DesignFeasibility StudiesFemaleFollow-Up StudiesHumansMaleMonitoring, PhysiologicSensory DeprivationTime FactorsTreatment Outcome

Identifiers

PMID31271842
PMCPMC7384242
OpenAlexW2954517224

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.